Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff

Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2...

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Vydáno v:	The Journal of hospital infection Ročník 106; číslo 1; s. 102 - 106
Hlavní autoři:	Martin, C., Montesinos, I., Dauby, N., Gilles, C., Dahma, H., Van Den Wijngaert, S., De Wit, S., Delforge, M., Clumeck, N., Vandenberg, O.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Elsevier Ltd 01.09.2020 The Healthcare Infection Society. Published by Elsevier Ltd
Témata:	Adult Antibodies Asymptomatic Asymptomatic Diseases Belgium Betacoronavirus - immunology Carriage Coronavirus Infections - immunology COVID-19 COVID-19 units Diagnostic Tests, Routine - standards Diagnostic Tests, Routine - statistics & numerical data Female Hospital staff Humans Male Middle Aged Pandemics Personnel, Hospital - statistics & numerical data Pneumonia, Viral - immunology Reverse Transcriptase Polymerase Chain Reaction - standards Reverse Transcriptase Polymerase Chain Reaction - statistics & numerical data Risk Assessment Risk Factors SARS-CoV-2 Seroepidemiologic Studies Belgium Antibodies Asymptomatic COVID-19 units Hospital staff Carriage
ISSN:	0195-6701, 1532-2939, 1532-2939
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Abstract	Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days.
AbstractList	Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days.Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days. Staff working in units that were highly exposed to coronavirus disease 2019 were invited to participate in a 6-month study on the carriage and seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The results from visits on Day 1 and Day 15 show that 41 cases of SARS-CoV-2 infection were confirmed by reverse transcriptase polymerase chain reaction and/or serology in 326 participants (overall infection rate 12.6%). The presence of comorbidities or symptoms at the time of sample collection was a risk factor for infection, but working as a physician/nurse was not a risk factor. Universal screening in high-risk units, irrespective of symptoms, allowed the identification of asymptomatic and potentially contagious infected workers, enabling them to self-isolate for 7 days.
Author	Van Den Wijngaert, S. Vandenberg, O. Dauby, N. Montesinos, I. Martin, C. Dahma, H. Clumeck, N. De Wit, S. Delforge, M. Gilles, C.
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SubjectTerms	Adult Antibodies Asymptomatic Asymptomatic Diseases Belgium Betacoronavirus - immunology Carriage Coronavirus Infections - immunology COVID-19 COVID-19 units Diagnostic Tests, Routine - standards Diagnostic Tests, Routine - statistics & numerical data Female Hospital staff Humans Male Middle Aged Pandemics Personnel, Hospital - statistics & numerical data Pneumonia, Viral - immunology Reverse Transcriptase Polymerase Chain Reaction - standards Reverse Transcriptase Polymerase Chain Reaction - statistics & numerical data Risk Assessment Risk Factors SARS-CoV-2 Seroepidemiologic Studies
Title	Dynamics of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk healthcare workers and hospital staff
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