Sertoli Cells Dictate Spermatogonial Stem Cell Niches in the Mouse Testis

Sustained spermatogenesis in adult males relies on the activity of spermatogonial stem cells (SSCs). In general, tissue-specific stem cell populations such as SSCs are influenced by contributions of support cells that form niche microenvironments. Previous studies have provided indirect evidence tha...

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Bibliographic Details
Published in:	Biology of reproduction Vol. 84; no. 4; pp. 639 - 645
Main Authors:	Oatley, M. J., Racicot, K. E., Oatley, J. M.
Format:	Journal Article
Language:	English
Published:	Madison, WI Society for the Study of Reproduction 01.04.2011 Society for the Study of Reproduction, Inc
Subjects:	Adult Stem Cells - cytology Adult Stem Cells - transplantation Animals Antithyroid Agents - pharmacology Biological and medical sciences Cell Count Cell Differentiation Cell Lineage Cell Proliferation - drug effects Fundamental and applied biological sciences. Psychology Male Mice Mice, 129 Strain Mice, Inbred C57BL Mice, Transgenic Propylthiouracil - pharmacology Seminiferous Tubules - anatomy & histology Seminiferous Tubules - blood supply Seminiferous Tubules - drug effects Sertoli Cells - cytology Sertoli Cells - drug effects Spermatogenesis Spermatogonia - cytology Spermatogonia - transplantation Testis - blood supply Testis - cytology Testis - drug effects Vertebrates: reproduction Sertoli cell spermatogonial stem cell Spermatogenesis Stem cell Rodentia Germinal cell Testicle Male genital system Sertoli cells Vertebrata Reproduction Mammalia Mouse Animal Spermatogonia niche
ISSN:	0006-3363, 1529-7268, 1529-7268
Online Access:	Get full text
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