Aortic elastic properties in patients with hypertensive response to exercise

The aim of this study was to evaluate whether there is a relationship between aortic elastic properties in patients with a suggestive response to treadmill exercise testing. The study group comprised 32 patients suggesting hypertensive response to exercise and 20 patients suggesting normal blood pre...

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Bibliographic Details
Published in:Circulation journal : official journal of the Japanese Circulation Society Vol. 71; no. 5; p. 727
Main Authors: Bitigen, Atila, Türkyilmaz, Erdem, Barutcu, Irfan, Kahveci, Gökhan, Tanboga, Ibrahim Halil, Aung, Soe Moe, Ozdemir, Nihal, Kaymaz, Cihangir
Format: Journal Article
Language:English
Published: Japan 2007
Subjects:
Aged
Aorta - physiopathology
Blood Pressure
Echocardiography
Elasticity
Exercise
Exercise Test
Female
Humans
Hypertension - diagnostic imaging
Hypertension - etiology
Hypertension - physiopathology
Male
Middle Aged
ISSN:1346-9843
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Summary:The aim of this study was to evaluate whether there is a relationship between aortic elastic properties in patients with a suggestive response to treadmill exercise testing. The study group comprised 32 patients suggesting hypertensive response to exercise and 20 patients suggesting normal blood pressure response to treadmill exercise testing. Baseline demographic characteristics were similar in both groups. However, the mean aortic stiffness index of patients suggesting hypertensive response to treadmill exercise testing was significantly higher (4.8+/-1.26 vs 2.36+/-1.09; p=0.001) whereas aortic distensibility was significantly lower (12.82 +/-5.84 vs 22.64+/-14.54; p=0.001) than the control group. The aortic strain of patients with hypertensive response to exercise was lower than the control group (12+/-3% vs 19.2+/-5%, p<0.001). The left ventricular mass (LVM) of these patients was also higher than control group (206.5+/-46.3 vs 134.2+/-19.97; p=0.01). A negative correlation between LVM and distensibility was found (r=-0.64; p=0.001) well as a positive correlation between LVM and aortic stiffness index (r=0.51; p=0.004) in patients suggesting hypertensive response to exercise. Pressure--rate product was also found to be correlated with LVM (r=0.47; p=0.006). Elastic properties of the aorta may be impaired in subjects showing exaggerated blood pressure response to exercise long before clinically manifest hypertension, particularly if the LVM is increased.
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ISSN:1346-9843
DOI:10.1253/circj.71.727