A multi-agent cell-based model for wound contraction

A mathematical model for wound contraction is presented. The model is based on a cell-based formalism where fibroblasts, myofibroblasts and the immune reaction are taken into account. The model is used to simulate contraction of a wound using point forces on the cell boundary and it also determines...

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Bibliographic Details
Published in:	Journal of biomechanics Vol. 49; no. 8; pp. 1388 - 1401
Main Authors:	Boon, W.M., Koppenol, D.C., Vermolen, F.J.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 24.05.2016 Elsevier Limited
Subjects:	Cell adhesion & migration Cell Movement Cell-based modelling Collagen Collagen - physiology Fibroblasts Fibroblasts - physiology Finite-element method Growth factors Humans Hybrid approach Hypothesis testing Immune system response Leukocytes - physiology Mathematical models Models, Biological Partial differential equations Physical Medicine and Rehabilitation Studies Wound contraction Wound healing Wound Healing - physiology Finite-element method Immune system response Wound contraction Hybrid approach Cell-based modelling
ISSN:	0021-9290, 1873-2380, 1873-2380
Online Access:	Get full text
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