Functional near-infrared spectroscopy-based diagnosis support system for distinguishing between mild and severe depression using machine learning approaches

Early diagnosis of depression is crucial for effective treatment. Our study utilizes functional near-infrared spectroscopy (fNIRS) and machine learning to accurately classify mild and severe depression, providing an objective auxiliary diagnostic tool for mental health workers. Develop prediction mo...

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Veröffentlicht in:Neurophotonics (Print) Jg. 11; H. 2; S. 025001
Hauptverfasser: Huang, Zhiyong, Liu, Man, Yang, Hui, Wang, Mengyao, Zhao, Yunlan, Han, Xiao, Chen, Huan, Feng, Yaju
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Society of Photo-Optical Instrumentation Engineers 01.04.2024
SPIE
Schlagworte:
Infrared spectroscopy
Machine learning
Medical research
Medicine, Experimental
Mental health
Mental illness
Research Papers
CEEMDAN-WPT
machine learning
functional near-infrared spectroscopy
severity of depression
ISSN:2329-423X, 2329-4248
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Zusammenfassung:Early diagnosis of depression is crucial for effective treatment. Our study utilizes functional near-infrared spectroscopy (fNIRS) and machine learning to accurately classify mild and severe depression, providing an objective auxiliary diagnostic tool for mental health workers. Develop prediction models to distinguish between severe and mild depression using fNIRS data. We collected the fNIRS data from 140 subjects and applied a complete ensemble empirical mode decomposition with an adaptive noise-wavelet threshold combined denoising method (CEEMDAN-WPT) to remove noise during the verbal fluency task. The temporal features (TF) and correlation features (CF) from 18 prefrontal lobe channels of subjects were extracted as predictors. Using recursive feature elimination with cross-validation, we identified optimal TF or CF and examined their role in distinguishing between severe and mild depression. Machine learning algorithms were used for classification. The combination of TF and CF as inputs for the prediction model yielded higher classification accuracy than using either TF or CF alone. Among the prediction models, the SVM-based model demonstrates excellent performance in nested cross-validation, achieving an accuracy rate of 92.8%. The proposed model can effectively distinguish mild depression from severe depression.
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Zhiyong Huang and Hui Yang are equally responsible for this study.
ISSN:2329-423X
2329-4248
DOI:10.1117/1.NPh.11.2.025001