Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

Human protein C is a natural anticoagulant factor, and a recombinant activated form of the molecule (rhAPC) is completing clinical evaluation for treatment of severe sepsis. Because of the pathophysiologic role of endothelial dysfunction in severe inflammatory disease and sepsis, we explored the pos...

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Bibliographic Details

Published in:	The Journal of biological chemistry Vol. 276; no. 14; p. 11199
Main Authors:	Joyce, D E, Gelbert, L, Ciaccia, A, DeHoff, B, Grinnell, B W
Format:	Journal Article
Language:	English
Published:	United States 06.04.2001
Subjects:	Apoptosis - genetics Endothelium, Vascular - pathology Endothelium, Vascular - physiology Gene Expression Profiling Gene Expression Regulation Humans Inflammation - genetics Inflammation - pathology Protein C - genetics
ISSN:	0021-9258
Online Access:	Get more information
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