Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

Human protein C is a natural anticoagulant factor, and a recombinant activated form of the molecule (rhAPC) is completing clinical evaluation for treatment of severe sepsis. Because of the pathophysiologic role of endothelial dysfunction in severe inflammatory disease and sepsis, we explored the pos...

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Vydané v:	The Journal of biological chemistry Ročník 276; číslo 14; s. 11199
Hlavní autori:	Joyce, D E, Gelbert, L, Ciaccia, A, DeHoff, B, Grinnell, B W
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 06.04.2001
Predmet:	Apoptosis - genetics Endothelium, Vascular - pathology Endothelium, Vascular - physiology Gene Expression Profiling Gene Expression Regulation Humans Inflammation - genetics Inflammation - pathology Protein C - genetics
ISSN:	0021-9258
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