Polystyrene microplastics mediate cell cycle arrest, apoptosis, and autophagy in the G2/M phase through ROS in grass carp kidney cells

Microplastics (MPs) have attracted widespread worldwide attention as a new pollutant. However, the role of reactive oxygen species (ROS) and cell cycle in nephrotoxicity induced by different concentrations of polystyrene microplastics (PS‐MPs) is unknown. This study used grass carp kidney cells (CIK...

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Vydané v:	Environmental toxicology Ročník 39; číslo 4; s. 1923 - 1935
Hlavní autori:	Lu, Hongmin, Hou, Lulu, Zhang, Yue, Guo, Tiantian, Wang, Yu, Xing, Mingwei
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Hoboken, USA John Wiley & Sons, Inc 01.04.2024 Wiley Subscription Services, Inc
Predmet:	Adenosine diphosphate ADP Animals antioxidant activity Apoptosis apoptosis and autophagy Autophagy B-lymphocytes Bcl-2 protein Biology Carp Caspase 3 - metabolism Caspase-3 Caspase-9 Cell cycle Cell Cycle Checkpoints Cell Division Cells CIK cells Ctenopharyngodon idella cyclin-dependent kinase Cytochrome c Cytochromes ecotoxicology G2/M cell cycle arrest Glutathione Humans Kidney - metabolism Kidneys Kinases Lymphoma Malondialdehyde Microplastics Microplastics - toxicity mitosis nephrotoxicity Oxidative stress Plastic pollution Plastics - pharmacology pollutants Poly(ADP-ribose) polymerase Poly(ADP-ribose) Polymerase Inhibitors - pharmacology Polystyrene polystyrene microplastic Polystyrene resins polystyrenes Polystyrenes - toxicity Protein-serine/threonine kinase Reactive oxygen species Reactive Oxygen Species - metabolism Ribose ROS Serine Superoxide dismutase Threonine Toxicology CIK cells apoptosis and autophagy polystyrene microplastic ROS G2/M cell cycle arrest
ISSN:	1520-4081, 1522-7278, 1522-7278
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