Dual role of autophagy in hallmarks of cancer

Evolutionarily conserved across eukaryotic cells, macroautophagy (herein autophagy) is an intracellular catabolic degradative process targeting damaged and superfluous cellular proteins, organelles, and other cytoplasmic components. Mechanistically, it involves formation of double-membrane vesicles...

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Bibliographic Details
Published in:	Oncogene Vol. 37; no. 9; pp. 1142 - 1158
Main Authors:	Singh, Shikha Satendra, Vats, Somya, Chia, Amelia Yi-Qian, Tan, Tuan Zea, Deng, Shuo, Ong, Mei Shan, Arfuso, Frank, Yap, Celestial T., Goh, Boon Cher, Sethi, Gautam, Huang, Ruby Yun-Ju, Shen, Han Ming, Manjithaya, Ravi, Kumar, Alan Prem
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.03.2018 Nature Publishing Group
Subjects:	631/67/2327 631/80/39 Animals Apoptosis Autophagy Autophagy (Cytology) Cancer Carcinogenesis Care and treatment Cell Biology Cell Transformation, Neoplastic - pathology Cytoplasm Eukaryotes Health aspects Human Genetics Humans Internal Medicine Lysosomes Medicine Medicine & Public Health Membrane vesicles Neoplasms - pathology Neurodegeneration Oncology Organelles Phagocytosis Phagosomes Physiological aspects Review Article Tumor suppression Tumorigenesis Singapore
ISSN:	0950-9232, 1476-5594, 1476-5594
Online Access:	Get full text
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