Nutraceutical Potential of Grape (Vitis vinifera L.) Seed Oil in Oxidative Stress, Inflammation, Obesity and Metabolic Alterations

Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65–75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatec...

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Vydáno v:Molecules (Basel, Switzerland) Ročník 28; číslo 23; s. 7811
Hlavní autoři: Di Pietro Fernandes, Carolina, Santana, Lidiani Figueiredo, dos Santos, Jair Rosa, Fernandes, Dayane Stéphanie, Hiane, Priscila Aiko, Pott, Arnildo, Freitas, Karine de Cássia, Bogo, Danielle, do Nascimento, Valter Aragão, Filiú, Wander Fernando de Oliveira, Asato, Marcel Arakaki, Guimarães, Rita de Cássia Avellaneda
Médium: Journal Article
Jazyk:angličtina
Vydáno: Switzerland MDPI AG 28.11.2023
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ISSN:1420-3049, 1420-3049
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Shrnutí:Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65–75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.4 mg), and gallic acid (77 µg), shows promise as a nutritional compound and is outstanding as a therapeutic substance with active properties for health, detected mainly by in vitro studies, as well as some in vivo studies. The benefits of consuming this oil include modulating the expression of antioxidant enzymes, anti-atherosclerotic and anti-inflammatory effects, and protection against oxidative cell damage and some types of cancer. However, experimental findings confirm that therapeutic functions remain scarce; thus, more studies are needed to determine the mechanisms of action involved in the indicated therapeutic qualities.
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ISSN:1420-3049
1420-3049
DOI:10.3390/molecules28237811