Nutraceutical Potential of Grape (Vitis vinifera L.) Seed Oil in Oxidative Stress, Inflammation, Obesity and Metabolic Alterations

Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65–75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatec...

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Vydáno v:	Molecules (Basel, Switzerland) Ročník 28; číslo 23; s. 7811
Hlavní autoři:	Di Pietro Fernandes, Carolina, Santana, Lidiani Figueiredo, dos Santos, Jair Rosa, Fernandes, Dayane Stéphanie, Hiane, Priscila Aiko, Pott, Arnildo, Freitas, Karine de Cássia, Bogo, Danielle, do Nascimento, Valter Aragão, Filiú, Wander Fernando de Oliveira, Asato, Marcel Arakaki, Guimarães, Rita de Cássia Avellaneda
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland MDPI AG 28.11.2023
Témata:	Antioxidants Cancer Carbohydrates Cocoa Enzymes Fatty acids Functional foods Grapes Health aspects Inflammation Leaves linoleic acid Lipids Metabolism Obesity Oxidative stress phenolics Phytochemicals Phytosterols plant oil Prevention Proteins resveratrol Seeds therapeutic potential Unsaturated fatty acids Vitamins Wines Brazil Europe Western Europe therapeutic potential inflammation linoleic acid resveratrol obesity oxidative stress plant oil phenolics
ISSN:	1420-3049, 1420-3049
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Abstract	Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65–75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.4 mg), and gallic acid (77 µg), shows promise as a nutritional compound and is outstanding as a therapeutic substance with active properties for health, detected mainly by in vitro studies, as well as some in vivo studies. The benefits of consuming this oil include modulating the expression of antioxidant enzymes, anti-atherosclerotic and anti-inflammatory effects, and protection against oxidative cell damage and some types of cancer. However, experimental findings confirm that therapeutic functions remain scarce; thus, more studies are needed to determine the mechanisms of action involved in the indicated therapeutic qualities.
AbstractList	Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65–75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.4 mg), and gallic acid (77 µg), shows promise as a nutritional compound and is outstanding as a therapeutic substance with active properties for health, detected mainly by in vitro studies, as well as some in vivo studies. The benefits of consuming this oil include modulating the expression of antioxidant enzymes, anti-atherosclerotic and anti-inflammatory effects, and protection against oxidative cell damage and some types of cancer. However, experimental findings confirm that therapeutic functions remain scarce; thus, more studies are needed to determine the mechanisms of action involved in the indicated therapeutic qualities. L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65-75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.4 mg), and gallic acid (77 µg), shows promise as a nutritional compound and is outstanding as a therapeutic substance with active properties for health, detected mainly by in vitro studies, as well as some in vivo studies. The benefits of consuming this oil include modulating the expression of antioxidant enzymes, anti-atherosclerotic and anti-inflammatory effects, and protection against oxidative cell damage and some types of cancer. However, experimental findings confirm that therapeutic functions remain scarce; thus, more studies are needed to determine the mechanisms of action involved in the indicated therapeutic qualities. Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65-75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.4 mg), and gallic acid (77 µg), shows promise as a nutritional compound and is outstanding as a therapeutic substance with active properties for health, detected mainly by in vitro studies, as well as some in vivo studies. The benefits of consuming this oil include modulating the expression of antioxidant enzymes, anti-atherosclerotic and anti-inflammatory effects, and protection against oxidative cell damage and some types of cancer. However, experimental findings confirm that therapeutic functions remain scarce; thus, more studies are needed to determine the mechanisms of action involved in the indicated therapeutic qualities.Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65-75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catechins (414 mg), epicatechins (130.4 mg), and gallic acid (77 µg), shows promise as a nutritional compound and is outstanding as a therapeutic substance with active properties for health, detected mainly by in vitro studies, as well as some in vivo studies. The benefits of consuming this oil include modulating the expression of antioxidant enzymes, anti-atherosclerotic and anti-inflammatory effects, and protection against oxidative cell damage and some types of cancer. However, experimental findings confirm that therapeutic functions remain scarce; thus, more studies are needed to determine the mechanisms of action involved in the indicated therapeutic qualities.
Audience	Academic
Author	Di Pietro Fernandes, Carolina Hiane, Priscila Aiko dos Santos, Jair Rosa Freitas, Karine de Cássia do Nascimento, Valter Aragão Bogo, Danielle Filiú, Wander Fernando de Oliveira Asato, Marcel Arakaki Santana, Lidiani Figueiredo Guimarães, Rita de Cássia Avellaneda Fernandes, Dayane Stéphanie Pott, Arnildo
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Snippet	Vitis vinifera L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty... L. (grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as...
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SubjectTerms	Antioxidants Cancer Carbohydrates Cocoa Enzymes Fatty acids Functional foods Grapes Health aspects Inflammation Leaves linoleic acid Lipids Metabolism Obesity Oxidative stress phenolics Phytochemicals Phytosterols plant oil Prevention Proteins resveratrol Seeds therapeutic potential Unsaturated fatty acids Vitamins Wines
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Title	Nutraceutical Potential of Grape (Vitis vinifera L.) Seed Oil in Oxidative Stress, Inflammation, Obesity and Metabolic Alterations
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