The Mini‐Organo: A rapid high‐throughput 3D coculture organotypic assay for oncology screening and drug development

Background The use of in vitro cell cultures is a powerful tool for obtaining key insights into the behaviour and response of cells to interventions in normal and disease situations. Unlike in vivo settings, in vitro experiments allow a fine‐tuned control of a range of microenvironmental elements in...

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Vydáno v:	Cancer reports Ročník 3; číslo 1; s. e1209 - n/a
Hlavní autoři:	Chitty, Jessica L., Skhinas, Joanna N., Filipe, Elysse C., Wang, Shan, Cupello, Carmen Rodriguez, Grant, Rhiannon D., Yam, Michelle, Papanicolaou, Michael, Major, Gretel, Zaratzian, Anaiis, Da Silva, Andrew M., Tayao, Michael, Vennin, Claire, Timpson, Paul, Madsen, Chris D., Cox, Thomas R.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States John Wiley and Sons Inc 01.02.2020
Témata:	3D model Animals Basic Medicine Cancer-Associated Fibroblasts - physiology cancer‐associated fibroblast Cell and Molecular Biology Cell- och molekylärbiologi coculture Coculture Techniques - methods Drug Development - methods drug screening Drug Screening Assays, Antitumor - methods extracellular matrix High-Throughput Screening Assays Humans Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Method Report Mice Neoplasm Invasiveness organotypic Rats cancer-associated fibroblast 3D model coculture organotypic drug screening extracellular matrix
ISSN:	2573-8348, 2573-8348
On-line přístup:	Získat plný text
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