The neglected role of insulin‐like growth factors in the maternal circulation regulating fetal growth

Maternal insulin‐like growth factors (IGFs) play a pivotal role in modulating fetal growth via their actions on both the mother and the placenta. Circulating IGFs influence maternal tissue growth and metabolism, thereby regulating nutrient availability for the growth of the conceptus. Maternal IGFs...

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Bibliographic Details
Published in:	The Journal of physiology Vol. 589; no. 1; pp. 7 - 20
Main Authors:	Sferruzzi‐Perri, A. N., Owens, J. A., Pringle, K. G., Roberts, C. T.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.01.2011 Wiley Subscription Services, Inc Blackwell Science Inc
Subjects:	Animals Birth weight Energy Metabolism Female Fetal Development Fetus - blood supply Fetus - metabolism Health risk assessment Humans Insulin-like growth factors Maternal Nutritional Physiological Phenomena Maternal-Fetal Exchange Placenta Placenta - blood supply Placenta - metabolism Placental Circulation Pregnancy Prenatal development Somatomedins - metabolism Topical Reviews
ISSN:	0022-3751, 1469-7793, 1469-7793
Online Access:	Get full text
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