Thoracic Aortic Aneurysm Growth: Role of Sex and Aneurysm Etiology
Background Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm etiology on TAA growth. Methods and Results Eig...
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| Vydáno v: | Journal of the American Heart Association Ročník 6; číslo 2 |
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| Hlavní autoři: | , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
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England
John Wiley and Sons Inc
03.02.2017
Wiley |
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| ISSN: | 2047-9980, 2047-9980 |
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| Abstract | Background
Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm etiology on TAA growth.
Methods and Results
Eighty‐two consecutive unoperated subjects with TAA who had serial aneurysm measurements were recruited. In multivariable linear regression the association of female sex with aneurysm growth rate was assessed after adjustment for potential confounders. We also tested the interaction term sex×aneurysm etiology in the prediction of TAA growth. Seventy‐four percent of subjects were men; mean±SD age was 62.4±11.9 years in men and 67.7±10.7 years in women (P=0.06). Forty‐seven (57%) subjects had degenerative TAAs, and the remainder had heritable TAAs. Absolute baseline aneurysm size and follow‐up time were not different between men and women. Aneurysm growth rate was 1.19±1.15 mm/y in women and 0.59±0.66 mm/y in men (P=0.02). Female sex remained significantly associated with greater aneurysm growth in multivariable analyses (β±SE: 0.35±0.12, P=0.005). In addition, female sex was associated with faster TAA growth only among those with degenerative TAA (β±SE: 0.33±0.08, P=0.0002) and not among those with heritable TAA (P=0.79), with a significant sex×etiology interaction (P=0.001).
Conclusions
TAA growth rates are greater in women than men, and this difference is specific to women with degenerative TAAs. Our findings may explain sex differences in TAA outcomes and provide a foundation for future investigations of this topic. |
|---|---|
| AbstractList | Background
Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm etiology on TAA growth.
Methods and Results
Eighty‐two consecutive unoperated subjects with TAA who had serial aneurysm measurements were recruited. In multivariable linear regression the association of female sex with aneurysm growth rate was assessed after adjustment for potential confounders. We also tested the interaction term sex×aneurysm etiology in the prediction of TAA growth. Seventy‐four percent of subjects were men; mean±SD age was 62.4±11.9 years in men and 67.7±10.7 years in women (P=0.06). Forty‐seven (57%) subjects had degenerative TAAs, and the remainder had heritable TAAs. Absolute baseline aneurysm size and follow‐up time were not different between men and women. Aneurysm growth rate was 1.19±1.15 mm/y in women and 0.59±0.66 mm/y in men (P=0.02). Female sex remained significantly associated with greater aneurysm growth in multivariable analyses (β±SE: 0.35±0.12, P=0.005). In addition, female sex was associated with faster TAA growth only among those with degenerative TAA (β±SE: 0.33±0.08, P=0.0002) and not among those with heritable TAA (P=0.79), with a significant sex×etiology interaction (P=0.001).
Conclusions
TAA growth rates are greater in women than men, and this difference is specific to women with degenerative TAAs. Our findings may explain sex differences in TAA outcomes and provide a foundation for future investigations of this topic. BackgroundThoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm etiology on TAA growth. Methods and ResultsEighty‐two consecutive unoperated subjects with TAA who had serial aneurysm measurements were recruited. In multivariable linear regression the association of female sex with aneurysm growth rate was assessed after adjustment for potential confounders. We also tested the interaction term sex×aneurysm etiology in the prediction of TAA growth. Seventy‐four percent of subjects were men; mean±SD age was 62.4±11.9 years in men and 67.7±10.7 years in women (P=0.06). Forty‐seven (57%) subjects had degenerative TAAs, and the remainder had heritable TAAs. Absolute baseline aneurysm size and follow‐up time were not different between men and women. Aneurysm growth rate was 1.19±1.15 mm/y in women and 0.59±0.66 mm/y in men (P=0.02). Female sex remained significantly associated with greater aneurysm growth in multivariable analyses (β±SE: 0.35±0.12, P=0.005). In addition, female sex was associated with faster TAA growth only among those with degenerative TAA (β±SE: 0.33±0.08, P=0.0002) and not among those with heritable TAA (P=0.79), with a significant sex×etiology interaction (P=0.001). ConclusionsTAA growth rates are greater in women than men, and this difference is specific to women with degenerative TAAs. Our findings may explain sex differences in TAA outcomes and provide a foundation for future investigations of this topic. Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm etiology on TAA growth.BACKGROUNDThoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm etiology on TAA growth.Eighty-two consecutive unoperated subjects with TAA who had serial aneurysm measurements were recruited. In multivariable linear regression the association of female sex with aneurysm growth rate was assessed after adjustment for potential confounders. We also tested the interaction term sex×aneurysm etiology in the prediction of TAA growth. Seventy-four percent of subjects were men; mean±SD age was 62.4±11.9 years in men and 67.7±10.7 years in women (P=0.06). Forty-seven (57%) subjects had degenerative TAAs, and the remainder had heritable TAAs. Absolute baseline aneurysm size and follow-up time were not different between men and women. Aneurysm growth rate was 1.19±1.15 mm/y in women and 0.59±0.66 mm/y in men (P=0.02). Female sex remained significantly associated with greater aneurysm growth in multivariable analyses (β±SE: 0.35±0.12, P=0.005). In addition, female sex was associated with faster TAA growth only among those with degenerative TAA (β±SE: 0.33±0.08, P=0.0002) and not among those with heritable TAA (P=0.79), with a significant sex×etiology interaction (P=0.001).METHODS AND RESULTSEighty-two consecutive unoperated subjects with TAA who had serial aneurysm measurements were recruited. In multivariable linear regression the association of female sex with aneurysm growth rate was assessed after adjustment for potential confounders. We also tested the interaction term sex×aneurysm etiology in the prediction of TAA growth. Seventy-four percent of subjects were men; mean±SD age was 62.4±11.9 years in men and 67.7±10.7 years in women (P=0.06). Forty-seven (57%) subjects had degenerative TAAs, and the remainder had heritable TAAs. Absolute baseline aneurysm size and follow-up time were not different between men and women. Aneurysm growth rate was 1.19±1.15 mm/y in women and 0.59±0.66 mm/y in men (P=0.02). Female sex remained significantly associated with greater aneurysm growth in multivariable analyses (β±SE: 0.35±0.12, P=0.005). In addition, female sex was associated with faster TAA growth only among those with degenerative TAA (β±SE: 0.33±0.08, P=0.0002) and not among those with heritable TAA (P=0.79), with a significant sex×etiology interaction (P=0.001).TAA growth rates are greater in women than men, and this difference is specific to women with degenerative TAAs. Our findings may explain sex differences in TAA outcomes and provide a foundation for future investigations of this topic.CONCLUSIONSTAA growth rates are greater in women than men, and this difference is specific to women with degenerative TAAs. Our findings may explain sex differences in TAA outcomes and provide a foundation for future investigations of this topic. Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm etiology on TAA growth. Eighty-two consecutive unoperated subjects with TAA who had serial aneurysm measurements were recruited. In multivariable linear regression the association of female sex with aneurysm growth rate was assessed after adjustment for potential confounders. We also tested the interaction term sex×aneurysm etiology in the prediction of TAA growth. Seventy-four percent of subjects were men; mean±SD age was 62.4±11.9 years in men and 67.7±10.7 years in women (P=0.06). Forty-seven (57%) subjects had degenerative TAAs, and the remainder had heritable TAAs. Absolute baseline aneurysm size and follow-up time were not different between men and women. Aneurysm growth rate was 1.19±1.15 mm/y in women and 0.59±0.66 mm/y in men (P=0.02). Female sex remained significantly associated with greater aneurysm growth in multivariable analyses (β±SE: 0.35±0.12, P=0.005). In addition, female sex was associated with faster TAA growth only among those with degenerative TAA (β±SE: 0.33±0.08, P=0.0002) and not among those with heritable TAA (P=0.79), with a significant sex×etiology interaction (P=0.001). TAA growth rates are greater in women than men, and this difference is specific to women with degenerative TAAs. Our findings may explain sex differences in TAA outcomes and provide a foundation for future investigations of this topic. |
| Author | Boodhwani, Munir Dick, Alexander Chan, Kwan‐Leung Cheung, Katie Beauchesne, Luc Coutinho, Thais |
| AuthorAffiliation | 3 Division of Cardiology University of Ottawa Heart Institute Ottawa Ontario Canada 2 Division of Cardiac Surgery University of Ottawa Heart Institute Ottawa Ontario Canada 1 School of Biomedical Sciences University of Ottawa Ontario Canada |
| AuthorAffiliation_xml | – name: 1 School of Biomedical Sciences University of Ottawa Ontario Canada – name: 2 Division of Cardiac Surgery University of Ottawa Heart Institute Ottawa Ontario Canada – name: 3 Division of Cardiology University of Ottawa Heart Institute Ottawa Ontario Canada |
| Author_xml | – sequence: 1 givenname: Katie surname: Cheung fullname: Cheung, Katie organization: University of Ottawa – sequence: 2 givenname: Munir surname: Boodhwani fullname: Boodhwani, Munir organization: University of Ottawa Heart Institute – sequence: 3 givenname: Kwan‐Leung surname: Chan fullname: Chan, Kwan‐Leung organization: University of Ottawa Heart Institute – sequence: 4 givenname: Luc surname: Beauchesne fullname: Beauchesne, Luc organization: University of Ottawa Heart Institute – sequence: 5 givenname: Alexander surname: Dick fullname: Dick, Alexander organization: University of Ottawa Heart Institute – sequence: 6 givenname: Thais surname: Coutinho fullname: Coutinho, Thais email: tcoutinho@ottawaheart.ca organization: University of Ottawa Heart Institute |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28159818$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1161/CIRCULATIONAHA.106.630400 10.1016/j.jvs.2004.08.035 10.1016/S0003-4975(97)00414-1 10.2214/ajr.146.2.309 10.1161/cir.0000000000000152 10.1016/S0003-4975(01)03236-2 10.1016/j.jvs.2012.04.053 10.1016/S0003-4975(02)04147-4 10.1002/bjs.5573 10.1161/CIRCULATIONAHA.107.702720 10.1053/j.semtcvs.2011.08.009 10.1016/j.jvs.2012.01.055 10.1016/j.athoracsur.2004.05.088 10.3310/hta17410 10.1136/heartjnl-2013-304129 10.1378/chest.117.5.1271 10.1002/bjs.6779 10.1016/j.athoracsur.2006.10.074 10.1161/01.CIR.0000130644.78677.2C 10.1161/res.90.3.251 10.1016/S0022-5223(97)70360-X 10.1016/j.echo.2014.11.015 10.1016/S1474-4422(11)70109-0 10.1016/S0741-5214(98)70319-2 10.1016/j.jacc.2012.08.997 10.1016/j.athoracsur.2005.06.026 10.1161/CIR.0b013e3181d4739e 10.1161/JAHA.114.001513 10.1016/j.jmbbm.2014.02.015 10.1016/j.cjca.2014.02.018 10.3171/2014.5.JNS132048 10.1210/jc.2009-1696 10.1002/bjs.8707 10.1016/j.ejvs.2004.11.015 |
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| References | 1997; 113 1998; 27 2010; 97 2004; 40 2015; 4 2002; 74 1997; 63 2002; 73 2000; 117 2013; 61 2010; 121 1970; 54 2011; 10 2007; 94 2004; 109 2012; 13 2012; 56 2012; 99 2005; 29 2006; 114 2006; 81 2015; 28 1986; 146 2007; 116 2013; 17 2004; 78 2015; 131 2007; 83 2011; 23 2002; 90 2014; 30 2014; 121 2014; 100 2014; 34 2010; 95 Gehan EA (e_1_3_3_18_2) 1970; 54 e_1_3_3_17_2 e_1_3_3_16_2 e_1_3_3_19_2 e_1_3_3_13_2 e_1_3_3_36_2 e_1_3_3_12_2 e_1_3_3_37_2 e_1_3_3_15_2 e_1_3_3_34_2 e_1_3_3_14_2 e_1_3_3_35_2 e_1_3_3_32_2 e_1_3_3_33_2 e_1_3_3_11_2 e_1_3_3_30_2 e_1_3_3_10_2 e_1_3_3_31_2 Manes A (e_1_3_3_21_2) 2012; 13 e_1_3_3_6_2 e_1_3_3_5_2 e_1_3_3_8_2 e_1_3_3_7_2 e_1_3_3_28_2 e_1_3_3_9_2 e_1_3_3_27_2 e_1_3_3_29_2 e_1_3_3_24_2 e_1_3_3_23_2 e_1_3_3_26_2 e_1_3_3_25_2 e_1_3_3_2_2 e_1_3_3_20_2 e_1_3_3_4_2 e_1_3_3_22_2 e_1_3_3_3_2 24583920 - J Mech Behav Biomed Mater. 2014 Jun;34:154-64 9580243 - J Vasc Surg. 1998 Mar;27(3):446-53 23122799 - J Am Coll Cardiol. 2013 Jan 8;61(1):96-103 17262754 - Br J Surg. 2007 Mar;94(3):310-4 12440685 - Ann Thorac Surg. 2002 Nov;74(5):S1877-80; discussion S1892-8 15197151 - Circulation. 2004 Jun 22;109(24):3014-21 24882528 - Can J Cardiol. 2014 Jun;30(6):577-89 3510513 - AJR Am J Roentgenol. 1986 Feb;146(2):309-14 9205145 - Ann Thorac Surg. 1997 Jun;63(6):1533-45 22622125 - G Ital Cardiol (Rome). 2012 Jun;13(6):448-60 24972124 - J Neurosurg. 2014 Sep;121(3):599-604 22389113 - Br J Surg. 2012 May;99(5):655-65 25520374 - Circulation. 2015 Jan 27;131(4):e29-322 25623219 - J Am Soc Echocardiogr. 2015 Feb;28(2):119-82 20013940 - Br J Surg. 2010 Jan;97(1):37-44 22041041 - Semin Thorac Cardiovasc Surg. 2011 Summer;23(2):124-5 20061425 - J Clin Endocrinol Metab. 2010 Mar;95(3):1123-30 11834007 - Ann Thorac Surg. 2002 Jan;73(1):17-27; discussion 27-8 15557917 - J Vasc Surg. 2004 Nov;40(5):1001-10 21641282 - Lancet Neurol. 2011 Jul;10(7):626-36 22503227 - J Vasc Surg. 2012 Aug;56(2):311-6 25609416 - J Am Heart Assoc. 2015 Jan 21;4(1):e001513 5527019 - Cancer Chemother Rep. 1970 Aug;54(4):225-35 15561045 - Ann Thorac Surg. 2004 Dec;78(6):2106-10; discussion 2110-1 22840907 - J Vasc Surg. 2012 Aug;56(2):565-71 24067626 - Health Technol Assess. 2013 Sep;17(41):1-118 15649720 - Eur J Vasc Endovasc Surg. 2005 Feb;29(2):145-9 17383337 - Ann Thorac Surg. 2007 Apr;83(4):1338-44 11861412 - Circ Res. 2002 Feb 22;90(3):251-62 16368358 - Ann Thorac Surg. 2006 Jan;81(1):169-77 9081092 - J Thorac Cardiovasc Surg. 1997 Mar;113(3):476-91; discussion 489-91 20233780 - Circulation. 2010 Apr 6;121(13):e266-369 17709637 - Circulation. 2007 Sep 4;116(10):1120-7 23813847 - Heart. 2014 Feb;100(4):295-302 10807810 - Chest. 2000 May;117(5):1271-8 17145990 - Circulation. 2006 Dec 12;114(24):2611-8 |
| References_xml | – volume: 56 start-page: 311 year: 2012 end-page: 316 article-title: Acute type B aortic dissection in the absence of aortic dilatation publication-title: J Vasc Surg – volume: 116 start-page: 1120 year: 2007 end-page: 1127 article-title: Aortic diameter > or = 5.5 cm is not a good predictor of type A aortic dissection: observations from the International Registry of Acute Aortic Dissection (IRAD) publication-title: Circulation – volume: 56 start-page: 565 year: 2012 end-page: 571 article-title: Natural history of thoracic aortic aneurysms publication-title: J Vasc Surg – volume: 113 start-page: 476 year: 1997 end-page: 491 article-title: What is the appropriate size criterion for resection of thoracic aortic aneurysms? publication-title: J Thorac Cardiovasc Surg – volume: 73 start-page: 17 year: 2002 end-page: 27 article-title: Yearly rupture or dissection rates for thoracic aortic aneurysms: simple prediction based on size publication-title: Ann Thorac Surg – volume: 27 start-page: 446 year: 1998 end-page: 453 article-title: Predictive factors for rupture of thoracoabdominal aortic aneurysm publication-title: J Vasc Surg – volume: 117 start-page: 1271 year: 2000 end-page: 1278 article-title: Epidemiology and clinicopathology of aortic dissection publication-title: Chest – volume: 81 start-page: 169 year: 2006 end-page: 177 article-title: Novel measurement of relative aortic size predicts rupture of thoracic aortic aneurysms publication-title: Ann Thorac Surg – volume: 29 start-page: 145 year: 2005 end-page: 149 article-title: Increased growth rate of abdominal aortic aneurysms in women. The Tromso study publication-title: Eur J Vasc Endovasc Surg – volume: 100 start-page: 295 year: 2014 end-page: 302 article-title: The association of genetic variants of matrix metalloproteinases with abdominal aortic aneurysm: a systematic review and meta‐analysis publication-title: Heart – volume: 4 start-page: e001513 year: 2015 article-title: Risk profiles for aortic dissection and ruptured or surgically treated aneurysms: a prospective cohort study publication-title: J Am Heart Assoc – volume: 131 start-page: e29 year: 2015 end-page: e322 article-title: Heart disease and stroke statistics—2015 update: a report from the American Heart Association publication-title: Circulation – volume: 74 start-page: S1877 year: 2002 end-page: S1880 article-title: Natural history of thoracic aortic aneurysms: indications for surgery, and surgical versus nonsurgical risks publication-title: Ann Thorac Surg – volume: 63 start-page: 1533 year: 1997 end-page: 1545 article-title: Prospective study of the natural history of thoracic aortic aneurysms publication-title: Ann Thorac Surg – volume: 28 start-page: 119 year: 2015 end-page: 182 article-title: Multimodality imaging of diseases of the thoracic aorta in adults: from the American Society of Echocardiography and the European Association of Cardiovascular Imaging: endorsed by the Society of Cardiovascular Computed Tomography and Society for Cardiovascular Magnetic Resonance publication-title: J Am Soc Echocardiogr – volume: 114 start-page: 2611 year: 2006 end-page: 2618 article-title: Thoracic aortic aneurysm and dissection: increasing prevalence and improved outcomes reported in a nationwide population‐based study of more than 14,000 cases from 1987 to 2002 publication-title: Circulation – volume: 94 start-page: 310 year: 2007 end-page: 314 article-title: Influence of sex on expansion rate of abdominal aortic aneurysms publication-title: Br J Surg – volume: 146 start-page: 309 year: 1986 end-page: 314 article-title: Magnetic resonance imaging of thoracic aortic aneurysms: comparison with other imaging methods publication-title: AJR Am J Roentgenol – volume: 30 start-page: 577 year: 2014 end-page: 589 article-title: Canadian Cardiovascular Society position statement on the management of thoracic aortic disease publication-title: Can J Cardiol – volume: 13 start-page: 448 year: 2012 end-page: 460 article-title: Female gender and pulmonary arterial hypertension: a complex relationship publication-title: G Ital Cardiol – volume: 83 start-page: 1338 year: 2007 end-page: 1344 article-title: Natural history of ascending aortic aneurysms in the setting of an unreplaced bicuspid aortic valve publication-title: Ann Thorac Surg – volume: 34 start-page: 154 year: 2014 end-page: 164 article-title: Impaired mechanics and matrix metalloproteinases/inhibitors expression in female ascending thoracic aortic aneurysms publication-title: J Mech Behav Biomed Mater – volume: 97 start-page: 37 year: 2010 end-page: 44 article-title: Growth rates of small abdominal aortic aneurysms correlate with clinical events publication-title: Br J Surg – volume: 121 start-page: 599 year: 2014 end-page: 604 article-title: Female sex as a risk factor for the growth of asymptomatic unruptured cerebral saccular aneurysms in elderly patients publication-title: J Neurosurg – volume: 10 start-page: 626 year: 2011 end-page: 636 article-title: Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta‐analysis publication-title: Lancet Neurol – volume: 95 start-page: 1123 year: 2010 end-page: 1130 article-title: Associations of total testosterone, sex hormone‐binding globulin, calculated free testosterone, and luteinizing hormone with prevalence of abdominal aortic aneurysm in older men publication-title: J Clin Endocrinol Metab – volume: 17 start-page: 1 year: 2013 end-page: 118 article-title: Systematic review and meta‐analysis of the growth and rupture rates of small abdominal aortic aneurysms: implications for surveillance intervals and their cost‐effectiveness publication-title: Health Technol Assess – volume: 90 start-page: 251 year: 2002 end-page: 262 article-title: Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly publication-title: Circ Res – volume: 109 start-page: 3014 year: 2004 end-page: 3021 article-title: Gender‐related differences in acute aortic dissection publication-title: Circulation – volume: 121 start-page: e266 year: 2010 end-page: e369 article-title: 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine publication-title: Circulation – volume: 99 start-page: 655 year: 2012 end-page: 665 article-title: Meta‐analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms publication-title: Br J Surg – volume: 40 start-page: 1001 year: 2004 end-page: 1010 article-title: Matrix metalloproteinase‐specific inhibition of Ca entry mechanisms of vascular contraction publication-title: J Vasc Surg – volume: 61 start-page: 96 year: 2013 end-page: 103 article-title: Sex differences in arterial stiffness and ventricular‐arterial interactions publication-title: J Am Coll Cardiol – volume: 54 start-page: 225 year: 1970 end-page: 235 article-title: Estimation of human body surface area from height and weight publication-title: Cancer Chemother Rep – volume: 23 start-page: 124 year: 2011 end-page: 125 article-title: Sex and gender in thoracic aortic aneurysms and dissection publication-title: Semin Thorac Cardiovasc Surg – volume: 78 start-page: 2106 year: 2004 end-page: 2110 article-title: Increased tissue microarray matrix metalloproteinase expression favors proteolysis in thoracic aortic aneurysms and dissections publication-title: Ann Thorac Surg – ident: e_1_3_3_3_2 doi: 10.1161/CIRCULATIONAHA.106.630400 – ident: e_1_3_3_32_2 doi: 10.1016/j.jvs.2004.08.035 – ident: e_1_3_3_2_2 doi: 10.1016/S0003-4975(97)00414-1 – ident: e_1_3_3_37_2 doi: 10.2214/ajr.146.2.309 – volume: 54 start-page: 225 year: 1970 ident: e_1_3_3_18_2 article-title: Estimation of human body surface area from height and weight publication-title: Cancer Chemother Rep – ident: e_1_3_3_35_2 doi: 10.1161/cir.0000000000000152 – ident: e_1_3_3_9_2 doi: 10.1016/S0003-4975(01)03236-2 – ident: e_1_3_3_5_2 doi: 10.1016/j.jvs.2012.04.053 – ident: e_1_3_3_6_2 doi: 10.1016/S0003-4975(02)04147-4 – volume: 13 start-page: 448 year: 2012 ident: e_1_3_3_21_2 article-title: Female gender and pulmonary arterial hypertension: a complex relationship publication-title: G Ital Cardiol – ident: e_1_3_3_24_2 doi: 10.1002/bjs.5573 – ident: e_1_3_3_10_2 doi: 10.1161/CIRCULATIONAHA.107.702720 – ident: e_1_3_3_22_2 doi: 10.1053/j.semtcvs.2011.08.009 – ident: e_1_3_3_20_2 doi: 10.1016/j.jvs.2012.01.055 – ident: e_1_3_3_29_2 doi: 10.1016/j.athoracsur.2004.05.088 – ident: e_1_3_3_15_2 doi: 10.3310/hta17410 – ident: e_1_3_3_30_2 doi: 10.1136/heartjnl-2013-304129 – ident: e_1_3_3_4_2 doi: 10.1378/chest.117.5.1271 – ident: e_1_3_3_14_2 doi: 10.1002/bjs.6779 – ident: e_1_3_3_7_2 doi: 10.1016/j.athoracsur.2006.10.074 – ident: e_1_3_3_11_2 doi: 10.1161/01.CIR.0000130644.78677.2C – ident: e_1_3_3_28_2 doi: 10.1161/res.90.3.251 – ident: e_1_3_3_8_2 doi: 10.1016/S0022-5223(97)70360-X – ident: e_1_3_3_19_2 doi: 10.1016/j.echo.2014.11.015 – ident: e_1_3_3_26_2 doi: 10.1016/S1474-4422(11)70109-0 – ident: e_1_3_3_13_2 doi: 10.1016/S0741-5214(98)70319-2 – ident: e_1_3_3_36_2 doi: 10.1016/j.jacc.2012.08.997 – ident: e_1_3_3_12_2 doi: 10.1016/j.athoracsur.2005.06.026 – ident: e_1_3_3_16_2 doi: 10.1161/CIR.0b013e3181d4739e – ident: e_1_3_3_34_2 doi: 10.1161/JAHA.114.001513 – ident: e_1_3_3_31_2 doi: 10.1016/j.jmbbm.2014.02.015 – ident: e_1_3_3_17_2 doi: 10.1016/j.cjca.2014.02.018 – ident: e_1_3_3_27_2 doi: 10.3171/2014.5.JNS132048 – ident: e_1_3_3_33_2 doi: 10.1210/jc.2009-1696 – ident: e_1_3_3_23_2 doi: 10.1002/bjs.8707 – ident: e_1_3_3_25_2 doi: 10.1016/j.ejvs.2004.11.015 – reference: 3510513 - AJR Am J Roentgenol. 1986 Feb;146(2):309-14 – reference: 9081092 - J Thorac Cardiovasc Surg. 1997 Mar;113(3):476-91; discussion 489-91 – reference: 24067626 - Health Technol Assess. 2013 Sep;17(41):1-118 – reference: 12440685 - Ann Thorac Surg. 2002 Nov;74(5):S1877-80; discussion S1892-8 – reference: 25609416 - J Am Heart Assoc. 2015 Jan 21;4(1):e001513 – reference: 17383337 - Ann Thorac Surg. 2007 Apr;83(4):1338-44 – reference: 17709637 - Circulation. 2007 Sep 4;116(10):1120-7 – reference: 17145990 - Circulation. 2006 Dec 12;114(24):2611-8 – reference: 22503227 - J Vasc Surg. 2012 Aug;56(2):311-6 – reference: 5527019 - Cancer Chemother Rep. 1970 Aug;54(4):225-35 – reference: 15197151 - Circulation. 2004 Jun 22;109(24):3014-21 – reference: 15649720 - Eur J Vasc Endovasc Surg. 2005 Feb;29(2):145-9 – reference: 20061425 - J Clin Endocrinol Metab. 2010 Mar;95(3):1123-30 – reference: 21641282 - Lancet Neurol. 2011 Jul;10(7):626-36 – reference: 17262754 - Br J Surg. 2007 Mar;94(3):310-4 – reference: 22389113 - Br J Surg. 2012 May;99(5):655-65 – reference: 23813847 - Heart. 2014 Feb;100(4):295-302 – reference: 25623219 - J Am Soc Echocardiogr. 2015 Feb;28(2):119-82 – reference: 10807810 - Chest. 2000 May;117(5):1271-8 – reference: 9580243 - J Vasc Surg. 1998 Mar;27(3):446-53 – reference: 22622125 - G Ital Cardiol (Rome). 2012 Jun;13(6):448-60 – reference: 9205145 - Ann Thorac Surg. 1997 Jun;63(6):1533-45 – reference: 16368358 - Ann Thorac Surg. 2006 Jan;81(1):169-77 – reference: 20013940 - Br J Surg. 2010 Jan;97(1):37-44 – reference: 25520374 - Circulation. 2015 Jan 27;131(4):e29-322 – reference: 24882528 - Can J Cardiol. 2014 Jun;30(6):577-89 – reference: 22840907 - J Vasc Surg. 2012 Aug;56(2):565-71 – reference: 15557917 - J Vasc Surg. 2004 Nov;40(5):1001-10 – reference: 11861412 - Circ Res. 2002 Feb 22;90(3):251-62 – reference: 24583920 - J Mech Behav Biomed Mater. 2014 Jun;34:154-64 – reference: 22041041 - Semin Thorac Cardiovasc Surg. 2011 Summer;23(2):124-5 – reference: 20233780 - Circulation. 2010 Apr 6;121(13):e266-369 – reference: 11834007 - Ann Thorac Surg. 2002 Jan;73(1):17-27; discussion 27-8 – reference: 24972124 - J Neurosurg. 2014 Sep;121(3):599-604 – reference: 15561045 - Ann Thorac Surg. 2004 Dec;78(6):2106-10; discussion 2110-1 – reference: 23122799 - J Am Coll Cardiol. 2013 Jan 8;61(1):96-103 |
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Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is... Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk... BackgroundThoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a... |
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| SubjectTerms | Aged aneurysm aorta Aortic Aneurysm, Thoracic - diagnosis Aortic Aneurysm, Thoracic - epidemiology Aortic Aneurysm, Thoracic - etiology Disease Progression Echocardiography Female Humans hypertension Incidence Magnetic Resonance Imaging Male Middle Aged Ontario - epidemiology Original Research Prognosis Retrospective Studies Risk Assessment - methods Risk Factors Sex Factors thoracic aortic aneurysm Tomography, X-Ray Computed women |
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| Title | Thoracic Aortic Aneurysm Growth: Role of Sex and Aneurysm Etiology |
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