Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Intrathecal immunoglobulin-G synthesis is a hallmark of multiple sclerosis (MS), which can be detected by oligoclonal IgG bands (OCB) or by κ-free light chains (κ-FLC) in cerebrospinal fluid. To perform a systematic review and meta-analysis to evaluate whether κ-FLC index has similar diagnostic valu...

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Bibliographic Details
Published in:	Multiple sclerosis Vol. 29; no. 2; p. 169
Main Authors:	Hegen, Harald, Walde, Janette, Berek, Klaus, Arrambide, Georgina, Gnanapavan, Sharmilee, Kaplan, Batia, Khalil, Michael, Saadeh, Ruba, Teunissen, Charlotte, Tumani, Hayrettin, Villar, Luisa M, Willrich, Maria Alice V, Zetterberg, Henrik, Deisenhammer, Florian
Format:	Journal Article
Language:	English
Published:	England 01.02.2023
Subjects:	Biomarkers - cerebrospinal fluid Demyelinating Diseases Humans Immunoglobulin G - cerebrospinal fluid Immunoglobulin kappa-Chains - cerebrospinal fluid Multiple Sclerosis - cerebrospinal fluid Multiple Sclerosis - diagnosis Oligoclonal Bands - cerebrospinal fluid intrathecal fraction multiple sclerosis meta-analysis diagnosis index Cerebrospinal fluid kappa free light chains biomarker systematic review clinically isolated syndrome
ISSN:	1477-0970, 1477-0970
Online Access:	Get more information
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