The effect of heat-treatment on SARS-CoV-2 viability and detection

•SARS-CoV-2 is not fully inactivated by heating to 56 °C or 60 °C for up to 60 min.•Complete inactivation occurred at 80 °C for 90 min or 95 °C for 1 or 5 min.•Heating SARS-CoV-2 to 80 °C for more than 30 min results in increased Ct values.•Significant variation in inactivation efficacy occurred bet...

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Bibliographic Details
Published in:	Journal of virological methods Vol. 290; p. 114087
Main Authors:	Burton, Jane, Love, Hannah, Richards, Kevin, Burton, Christopher, Summers, Sian, Pitman, James, Easterbrook, Linda, Davies, Katherine, Spencer, Peter, Killip, Marian, Cane, Patricia, Bruce, Christine, Roberts, Allen D.G.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.04.2021 Published by Elsevier B.V
Subjects:	biosafety COVID-19 - diagnosis COVID-19 Nucleic Acid Testing heat Heat inactivation heat treatment Hot Temperature Humans SARS-CoV-2 SARS-CoV-2 - isolation & purification SARS-CoV-2 - physiology Sensitivity and Specificity Severe acute respiratory syndrome coronavirus 2 temperature Time Factors viability viral load virus culture Virus Inactivation viruses Heat inactivation SARS-CoV-2
ISSN:	0166-0934, 1879-0984, 1879-0984
Online Access:	Get full text
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