Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status

Onset of chronic periodontitis is associated with an aberrant polymicrobial community, termed dysbiosis. Findings regarding its etiology obtained using high-throughput sequencing technique suggested that dysbiosis holds a conserved metabolic signature as an emergent property. The purpose of this stu...

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Bibliographic Details
Published in:	Scientific reports Vol. 7; no. 1; p. 42818
Main Authors:	Sakanaka, Akito, Kuboniwa, Masae, Hashino, Ei, Bamba, Takeshi, Fukusaki, Eiichiro, Amano, Atsuo
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 21.02.2017 Nature Publishing Group
Subjects:	631/45/320 692/53/2421 692/699/255/1318 Adult Area Under Curve Arginine Biomarkers Biomarkers - metabolism Butyric acid Cadaverine Cadaverine - metabolism Chronic Periodontitis - metabolism Chronic Periodontitis - pathology Dental plaque Dental Plaque - metabolism Dysbacteriosis Ethanolamine Etiology Female Humanities and Social Sciences Humans Inflammation Lysine Male Metabolism Metabolites Metabolomics Middle Aged multidisciplinary Next-generation sequencing Periodontitis Phenylpropionates - metabolism Proline ROC Curve Saliva Saliva - metabolism Science Severity of Illness Index Uric acid
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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