Quantitative Analysis of Porcine Endogenous Retroviruses in Different Organs of Transgenic Pigs Generated for Xenotransplantation

The pig appears to be the most promising animal donor of organs for use in human recipients. Among several types of pathogens found in pigs, one of the greatest problems is presented by porcine endogenous retroviruses (PERVs). Screening of the source pig herd for PERVs should include analysis of bot...

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Vydané v:	Current microbiology Ročník 67; číslo 4; s. 505 - 514
Hlavní autori:	Mazurek, Urszula, Kimsa, Magdalena C., Strzalka-Mrozik, Barbara, Kimsa, Malgorzata W., Adamska, Jolanta, Lipinski, Daniel, Zeyland, Joanna, Szalata, Marlena, Slomski, Ryszard, Jura, Jacek, Smorag, Zdzislaw, Nowak, Roman, Gola, Joanna
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Boston Springer US 01.10.2013 Springer Nature B.V
Predmet:	alpha-galactosidase Animals Animals, Genetically Modified Animals, Genetically Modified - virology Biomedical and Life Sciences Biotechnology Blood Blood - virology Cardiac muscle classification Deoxyribonucleic acid DNA Endogenous Retroviruses Endogenous Retroviruses - classification Endogenous Retroviruses - genetics Endogenous Retroviruses - isolation & purification Gene Dosage genes genetics heart Heart - virology herds Hogs Humans isolation & purification Life Sciences liver Liver - virology Microbiology Muscles Muscles - virology Organs pathogens quantitative analysis Retrovirus Ribonucleic acid risk RNA screening Skin Skin - virology Swine Swine - virology Transgenic animals Transplantation, Heterologous Viral Proteins Viral Proteins - genetics virology Viruses Xenotransplantation Porcine Tissue Fucosyltransferase Gene Xenograft Rejection Human Recipient Perv Infection
ISSN:	0343-8651, 1432-0991, 1432-0991
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