Molecular digital data storage using DNA

Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review...

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Vydáno v:	Nature reviews. Genetics Ročník 20; číslo 8; s. 456 - 466
Hlavní autoři:	Ceze, Luis, Nivala, Jeff, Strauss, Karin
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 01.08.2019 Nature Publishing Group
Témata:	631/208/514/1948 631/337/151/1431 631/553/2720 631/92/147 639/301/1005/1008 639/925/926/1047 Agriculture Analysis Animal Genetics and Genomics Animals Biomedical and Life Sciences Biomedicine Biotechnology Biotechnology - methods Cancer Research Deoxyribonucleic acid DNA DNA - genetics DNA sequencing Gene expression Gene Function Human Genetics Humans Information storage Information storage and retrieval Information Storage and Retrieval - methods Nucleotide sequencing Review Article
ISSN:	1471-0056, 1471-0064, 1471-0064
On-line přístup:	Získat plný text
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Abstract	Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology. Throughout evolution, DNA has been the primary medium of biological information storage. In this article, Ceze, Nivala and Strauss discuss how DNA can be adopted as a storage medium for custom data, as a potential future complement to current data storage media such as computer hard disks, optical disks and tape. They discuss strategies for coding, decoding and error correction and give examples of implementation both in vitro and in vivo.
AbstractList	Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology. Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology. Throughout evolution, DNA has been the primary medium of biological information storage. In this article, Ceze, Nivala and Strauss discuss how DNA can be adopted as a storage medium for custom data, as a potential future complement to current data storage media such as computer hard disks, optical disks and tape. They discuss strategies for coding, decoding and error correction and give examples of implementation both in vitro and in vivo. Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology.Throughout evolution, DNA has been the primary medium of biological information storage. In this article, Ceze, Nivala and Strauss discuss how DNA can be adopted as a storage medium for custom data, as a potential future complement to current data storage media such as computer hard disks, optical disks and tape. They discuss strategies for coding, decoding and error correction and give examples of implementation both in vitro and in vivo. Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology.Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology.
Audience	Academic
Author	Strauss, Karin Ceze, Luis Nivala, Jeff
Author_xml	– sequence: 1 givenname: Luis orcidid: 0000-0002-1377-6217 surname: Ceze fullname: Ceze, Luis email: luisceze@cs.washington.edu organization: Paul G. Allen School of Computer Science and Engineering, University of Washington – sequence: 2 givenname: Jeff orcidid: 0000-0002-8210-5417 surname: Nivala fullname: Nivala, Jeff organization: Paul G. Allen School of Computer Science and Engineering, University of Washington – sequence: 3 givenname: Karin surname: Strauss fullname: Strauss, Karin organization: Paul G. Allen School of Computer Science and Engineering, University of Washington, Microsoft Research
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/31068682$$D View this record in MEDLINE/PubMed
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ContentType	Journal Article
Copyright	Springer Nature Limited 2019 COPYRIGHT 2019 Nature Publishing Group Springer Nature Limited 2019.
Copyright_xml	– notice: Springer Nature Limited 2019 – notice: COPYRIGHT 2019 Nature Publishing Group – notice: Springer Nature Limited 2019.
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Title	Molecular digital data storage using DNA
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