Molecular digital data storage using DNA

Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review...

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Bibliographic Details
Published in:Nature reviews. Genetics Vol. 20; no. 8; pp. 456 - 466
Main Authors: Ceze, Luis, Nivala, Jeff, Strauss, Karin
Format: Journal Article
Language:English
Published: England Nature Publishing Group 01.08.2019
Subjects:
Animals
Biotechnology
Biotechnology - methods
Deoxyribonucleic acid
DNA
DNA - genetics
Humans
Information storage
Information Storage and Retrieval - methods
ISSN:1471-0056, 1471-0064, 1471-0064
Online Access:Get full text
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Summary:Molecular data storage is an attractive alternative for dense and durable information storage, which is sorely needed to deal with the growing gap between information production and the ability to store data. DNA is a clear example of effective archival data storage in molecular form. In this Review, we provide an overview of the process, the state of the art in this area and challenges for mainstream adoption. We also survey the field of in vivo molecular memory systems that record and store information within the DNA of living cells, which, together with in vitro DNA data storage, lie at the growing intersection of computer systems and biotechnology.
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ISSN:1471-0056
1471-0064
1471-0064
DOI:10.1038/s41576-019-0125-3