Structural architecture of the human long non-coding RNA, steroid receptor RNA activator

While functional roles of several long non-coding RNAs (lncRNAs) have been determined, the molecular mechanisms are not well understood. Here, we report the first experimentally derived secondary structure of a human lncRNA, the steroid receptor RNA activator (SRA), 0.87 kB in size. The SRA RNA is a...

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Veröffentlicht in:	Nucleic acids research Jg. 40; H. 11; S. 5034 - 5051
Hauptverfasser:	Novikova, Irina V., Hennelly, Scott P., Sanbonmatsu, Karissa Y.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 01.06.2012
Schlagworte:	Alternative splicing Amino Acid Sequence Animals Base Sequence BASIC BIOLOGICAL SCIENCES Biochemistry & Molecular Biology Breast cancer Carrier Proteins - biosynthesis Carrier Proteins - genetics Coevolution Conserved Sequence Evolution Evolution, Molecular Humans Mice Molecular modelling Molecular Sequence Data Mutation non-coding RNA Nucleic Acid Conformation Nucleotide sequence Nucleotides - chemistry Protein structure Ribonuclease Ribonucleases RNA RNA, Long Noncoding RNA, Untranslated - chemistry Secondary structure Sequence Alignment Sex hormones Steroid hormone receptors Translation
ISSN:	0305-1048, 1362-4962, 1362-4962
Online-Zugang:	Volltext
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