Next-Generation Sequencing: From Basic Research to Diagnostics

Background: For the past 30 years, the Sanger method has been the dominant approach and gold standard for DNA sequencing. The commercial launch of the first massively parallel pyrosequencing platform in 2005 ushered in the new era of high-throughput genomic analysis now referred to as next-generatio...

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Bibliographic Details
Published in:	Clinical chemistry (Baltimore, Md.) Vol. 55; no. 4; pp. 641 - 658
Main Authors:	Voelkerding, Karl V, Dames, Shale A, Durtschi, Jacob D
Format:	Journal Article
Language:	English
Published:	Washington, DC Am Assoc Clin Chem 01.04.2009 American Association for Clinical Chemistry Oxford University Press
Subjects:	Accuracy Analytical, structural and metabolic biochemistry Animals Base Sequence - genetics Bioinformatics Biological and medical sciences Biomedical Research - methods Data processing Deoxyribonucleic acid DNA Fundamental and applied biological sciences. Psychology Genomics Human subjects Humans Industrial development Investigative techniques, diagnostic techniques (general aspects) Life sciences Medical sciences Molecular Diagnostic Techniques - methods Peer Review, Research - methods Software Technological change Validation studies Nucleotide sequence Clinical biology Biochemistry Diagnosis Fundamental research Molecular biology Sequencing
ISSN:	0009-9147, 1530-8561, 1530-8561
Online Access:	Get full text
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