Insulin-Like Growth Factor, Inflammation, and MRI Markers of Alzheimer's Disease in Predominantly Middle-Aged Adults

Insulin-like growth factor 1 (IGF-1) signaling has been implicated in Alzheimer's disease pathogenesis, and further evidence suggests inflammation can be a moderator of this association. However, most research to date has been conducted on older adults. To investigate the association of serum I...

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Veröffentlicht in:	Journal of Alzheimer's disease Jg. 88; H. 1; S. 311
Hauptverfasser:	Wittfeld, Katharina, Raman, Mekala R, Conner, Sarah C, Aslam, Asra, Teumer, Alexander, Nauck, Matthias, Hosten, Norbert, Habes, Mohamad, DeCarli, Charles, Vasan, Ramachandran S, Beiser, Alexa S, Himali, Jayandra J, Seshadri, Sudha, Grabe, Hans J, Satizabal, Claudia L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.01.2022
Schlagworte:	Adult Alzheimer Disease - diagnostic imaging Biomarkers C-Reactive Protein - metabolism Female Humans Inflammation - diagnostic imaging Insulin-Like Growth Factor Binding Protein 3 Insulin-Like Growth Factor I - analysis Magnetic Resonance Imaging Male Middle Aged epidemiology C-reactive protein cohort study hippocampus Alzheimer’s disease endophenotype insulin-like growth factor neuroimaging white matter hyperintensity
ISSN:	1875-8908, 1875-8908
Online-Zugang:	Weitere Angaben
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