Fatigue-induced increase in intracortical communication between mid/anterior insular and motor cortex during cycling exercise

In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant‐load test at 60% peak oxygen consumption (VO2peak) until volitional exhaustion, electroencephalogr...

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Vydáno v:	The European journal of neuroscience Ročník 34; číslo 12; s. 2035 - 2042
Hlavní autoři:	Hilty, Lea, Langer, Nicolas, Pascual-Marqui, Roberto, Boutellier, Urs, Lutz, Kai
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Oxford, UK Blackwell Publishing Ltd 01.12.2011
Témata:	Adult Cerebral Cortex - anatomy & histology Cerebral Cortex - physiology EEG Electroencephalography exercise Exercise - physiology homeostatic functions Humans lagged phase synchronization Male Motor Cortex - physiology Muscle Fatigue - physiology Nerve Net - anatomy & histology Nerve Net - physiology supraspinal fatigue Young Adult
ISSN:	0953-816X, 1460-9568, 1460-9568
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Abstract	In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant‐load test at 60% peak oxygen consumption (VO2peak) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact‐free periods of 1‐min duration. To quantify fatigue‐induced intracortical communication, mean intra‐hemispheric lagged phase synchronization between mid/anterior insular and motor cortex was calculated: (i) at the beginning of cycling; (ii) at the end of cycling; and (iii) during recovery cycling. Results revealed significantly increased lagged phase synchronization at the end of cycling, which returned to baseline during recovery cycling after subjects’ cessation of exercise. Following previous imaging studies reporting the mid/anterior insular cortex as an essential instance processing a variety of sensory stimuli and signalling forthcoming physiological threat, our results provide further evidence that during a fatiguing exercise this structure might not only integrate and evaluate sensory information from the periphery, but also act in communication with the motor cortex. To the best of our knowledge, this is the first study to empirically demonstrate that muscle fatigue leads to changes in interaction between structures of a brain’s neural network. In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant‐load test at 60% peak oxygen consumption (VO2peak) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact‐free periods of 1‐min duration.
AbstractList	In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant-load test at 60% peak oxygen consumption (VO2peak) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact-free periods of 1-min duration. To quantify fatigue-induced intracortical communication, mean intra-hemispheric lagged phase synchronization between mid/anterior insular and motor cortex was calculated: (i) at the beginning of cycling; (ii) at the end of cycling; and (iii) during recovery cycling. Results revealed significantly increased lagged phase synchronization at the end of cycling, which returned to baseline during recovery cycling after subjects' cessation of exercise. Following previous imaging studies reporting the mid/anterior insular cortex as an essential instance processing a variety of sensory stimuli and signalling forthcoming physiological threat, our results provide further evidence that during a fatiguing exercise this structure might not only integrate and evaluate sensory information from the periphery, but also act in communication with the motor cortex. To the best of our knowledge, this is the first study to empirically demonstrate that muscle fatigue leads to changes in interaction between structures of a brain's neural network. In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant-load test at 60% peak oxygen consumption (VO2peak) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact-free periods of 1-min duration. In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant-load test at 60% peak oxygen consumption (VO(2peak)) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact-free periods of 1-min duration. To quantify fatigue-induced intracortical communication, mean intra-hemispheric lagged phase synchronization between mid/anterior insular and motor cortex was calculated: (i) at the beginning of cycling; (ii) at the end of cycling; and (iii) during recovery cycling. Results revealed significantly increased lagged phase synchronization at the end of cycling, which returned to baseline during recovery cycling after subjects' cessation of exercise. Following previous imaging studies reporting the mid/anterior insular cortex as an essential instance processing a variety of sensory stimuli and signalling forthcoming physiological threat, our results provide further evidence that during a fatiguing exercise this structure might not only integrate and evaluate sensory information from the periphery, but also act in communication with the motor cortex. To the best of our knowledge, this is the first study to empirically demonstrate that muscle fatigue leads to changes in interaction between structures of a brain's neural network.In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant-load test at 60% peak oxygen consumption (VO(2peak)) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact-free periods of 1-min duration. To quantify fatigue-induced intracortical communication, mean intra-hemispheric lagged phase synchronization between mid/anterior insular and motor cortex was calculated: (i) at the beginning of cycling; (ii) at the end of cycling; and (iii) during recovery cycling. Results revealed significantly increased lagged phase synchronization at the end of cycling, which returned to baseline during recovery cycling after subjects' cessation of exercise. Following previous imaging studies reporting the mid/anterior insular cortex as an essential instance processing a variety of sensory stimuli and signalling forthcoming physiological threat, our results provide further evidence that during a fatiguing exercise this structure might not only integrate and evaluate sensory information from the periphery, but also act in communication with the motor cortex. To the best of our knowledge, this is the first study to empirically demonstrate that muscle fatigue leads to changes in interaction between structures of a brain's neural network. In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant‐load test at 60% peak oxygen consumption (VO2peak) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact‐free periods of 1‐min duration. To quantify fatigue‐induced intracortical communication, mean intra‐hemispheric lagged phase synchronization between mid/anterior insular and motor cortex was calculated: (i) at the beginning of cycling; (ii) at the end of cycling; and (iii) during recovery cycling. Results revealed significantly increased lagged phase synchronization at the end of cycling, which returned to baseline during recovery cycling after subjects’ cessation of exercise. Following previous imaging studies reporting the mid/anterior insular cortex as an essential instance processing a variety of sensory stimuli and signalling forthcoming physiological threat, our results provide further evidence that during a fatiguing exercise this structure might not only integrate and evaluate sensory information from the periphery, but also act in communication with the motor cortex. To the best of our knowledge, this is the first study to empirically demonstrate that muscle fatigue leads to changes in interaction between structures of a brain’s neural network. In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant‐load test at 60% peak oxygen consumption (VO2peak) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact‐free periods of 1‐min duration. In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16 healthy male subjects performing a constant-load test at 60% peak oxygen consumption (VO(2peak)) until volitional exhaustion, electroencephalography data were analysed during repetitive, artefact-free periods of 1-min duration. To quantify fatigue-induced intracortical communication, mean intra-hemispheric lagged phase synchronization between mid/anterior insular and motor cortex was calculated: (i) at the beginning of cycling; (ii) at the end of cycling; and (iii) during recovery cycling. Results revealed significantly increased lagged phase synchronization at the end of cycling, which returned to baseline during recovery cycling after subjects' cessation of exercise. Following previous imaging studies reporting the mid/anterior insular cortex as an essential instance processing a variety of sensory stimuli and signalling forthcoming physiological threat, our results provide further evidence that during a fatiguing exercise this structure might not only integrate and evaluate sensory information from the periphery, but also act in communication with the motor cortex. To the best of our knowledge, this is the first study to empirically demonstrate that muscle fatigue leads to changes in interaction between structures of a brain's neural network.
Author	Lutz, Kai Boutellier, Urs Langer, Nicolas Hilty, Lea Pascual-Marqui, Roberto
Author_xml	– sequence: 1 givenname: Lea surname: Hilty fullname: Hilty, Lea organization: Exercise Physiology, Institute of Human Movement Sciences, ETH Zurich, Zurich, Switzerland – sequence: 2 givenname: Nicolas surname: Langer fullname: Langer, Nicolas organization: Institute of Psychology, Department of Neuropsychology, University of Zurich, Switzerland – sequence: 3 givenname: Roberto surname: Pascual-Marqui fullname: Pascual-Marqui, Roberto organization: The KEY Institute for Brain-Mind Research, University Hospital of Psychiatry, Zurich, Switzerland – sequence: 4 givenname: Urs surname: Boutellier fullname: Boutellier, Urs organization: Exercise Physiology, Institute of Human Movement Sciences, ETH Zurich, Zurich, Switzerland – sequence: 5 givenname: Kai surname: Lutz fullname: Lutz, Kai organization: Institute of Psychology, Department of Neuropsychology, University of Zurich, Switzerland
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/22097899$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1152/ajplegacy.1976.231.2.430 10.1016/S1388-2457(00)00428-4 10.1016/j.brainres.2008.12.061 10.1016/j.pain.2003.12.029 10.1007/s004240100515 10.1136/bjsm.2003.010330 10.1152/jn.2002.88.3.1500 10.1038/72131 10.1152/jappl.2001.91.5.2017 10.1016/0013-4694(74)90005-4 10.1152/jn.00609.2001 10.1113/jphysiol.1996.sp021163 10.1136/bjsm.2003.009852 10.1098/rsta.2011.0081 10.1016/S0022-3999(02)00326-4 10.1073/pnas.96.8.4569 10.1113/expphysiol.2010.056226 10.1155/2010/671421 10.1097/00000441-193501000-00001 10.1113/jphysiol.1996.sp021164 10.1016/j.clinph.2004.04.029 10.1523/JNEUROSCI.2516-10.2010 10.1073/pnas.98.4.2029 10.3109/00207458808985694 10.1038/nn1527 10.1016/S0166-2236(03)00123-1 10.1162/003355397555253 10.1152/jn.1983.50.1.313 10.1016/j.neuroimage.2006.09.024 10.1002/cne.902710307 10.1016/j.jtherbio.2004.08.047 10.1002/hbm.20346 10.1152/japplphysiol.91324.2008 10.1007/s00421-004-1283-2 10.1016/S1388-2457(02)00030-5 10.1002/ana.410440516 10.1111/j.1469-7793.2000.00793.x 10.1038/372770a0 10.1080/026870399402325 10.1073/pnas.98.4.2035 10.1073/pnas.96.14.7668 10.1016/S0013-4694(97)00105-3 10.1093/cercor/6.3.342 10.1016/S1053-8119(03)00286-6 10.1152/jn.00821.2002 10.1002/mds.1042 10.1007/978-1-4615-5351-9_17 10.1016/S0959-4388(03)00090-4 10.1109/NSSMIC.1993.373602 10.1016/j.pain.2005.11.003 10.1016/S0006-8993(02)03665-X 10.1016/j.neuroimage.2005.12.003 10.1016/j.physbeh.2009.07.010 10.1126/science.1100907 10.1016/j.apergo.2010.01.008 10.1113/jphysiol.2007.140426 10.1136/bjsm.2003.010645
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References	Lou, J.S., Kearns, G., Oken, B., Sexton, G. & Nutt, J. (2001) Exacerbated physical fatigue and mental fatigue in Parkinson's disease. Mov. Disord., 16, 190-196. Henderson, L.A., Bandler, R., Gandevia, S.C. & Macefield, V.G. (2006) Distinct forebrain activity patterns during deep versus superficial pain. Pain, 120, 286-296. Marcora, S.M., Staiano, W. & Manning, V. (2009) Mental fatigue impairs physical performance in humans. J. Appl. Physiol., 106, 857-864. Jurcak, V., Tsuzuki, D. & Dan, I. (2007) 10/20, 10/10, and 10/5 systems revisited: their validity as relative head-surface-based positioning systems. Neuroimage, 34, 1600-1611. Evans, K.C., Banzett, R.B., Adams, L., McKay, L., Frackowiak, R.S. & Corfield, D.R. (2002) BOLD fMRI identifies limbic, paralimbic, and cerebellar activation during air hunger. J. Neurophysiol., 88, 1500-1511. Wilson, L.B., Andrew, D. & Craig, A.D. (2002) Activation of spinobulbar lamina I neurons by static muscle contraction. J. Neurophysiol., 87, 1641-1645. Rasmussen, P., Stie, H., Nybo, L. & Nielsen, B. (2004) Heat induced fatigue and changes of the EEG is not related to reduced perfusion of the brain during prolonged exercise in humans. J. Therm. Biol., 29, 731-737. Bigland-Ritchie, B., Johansson, R., Lippold, O.C. & Woods, J.J. (1983) Contractile speed and EMG changes during fatigue of sustained maximal voluntary contractions. J. Neurophysiol., 50, 313-324. Tajima, S., Yamamoto, S., Tanaka, M., Kataoka, Y., Iwase, M., Yoshikawa, E., Okada, H., Onoe, H., Tsukada, H., Kuratsune, H., Ouchi, Y. & Watanabe, Y. (2010) Medial orbitofrontal cortex is associated with fatigue sensation. Neurol. Res. Int., doi: 10.1155/2010/671421 [Epub ahead of print]. Pascual-Marqui, R.D., Lehmann, D., Koukkou, M., Kochi, K., Anderer, P., Saletu, B., Tanaka, H., Hirata, K., John, E.R., Prichep, L., Biscay-Lirio, R. & Kinoshita, T. (2011) Assessing interactions in the brain with exact low resolution electromagnetic tomography (eLORETA). Philos. Trans. R. Soc. Lond. A, 369, 3768-3784. Reiman, E.M. (1997) The application of positron emission tomography to the study of normal and pathologic emotions. J. Clin. Psychiatry, 58(Suppl 16), 4-12. Pascual-Marqui, R.D. (2002) Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. Methods Find. Exp. Clin. Pharmacol., 24(Suppl D), 5-12. Pfurtscheller, G., Brunner, C., Schlogl, A. & Lopes da Silva, F.H. (2006) Mu rhythm (de)synchronization and EEG single-trial classification of different motor imagery tasks. Neuroimage, 31, 153-159. Taylor, J.L., Butler, J.E., Allen, G.M. & Gandevia, S.C. (1996) Changes in motor cortical excitability during human muscle fatigue. J. Physiol., 490, 519-528. Craig, A.D. (2003a) Interoception: the sense of the physiological condition of the body. Curr. Opin. Neurobiol., 13, 500-505. Stam, C.J., Nolte, G. & Daffertshofer, A. (2007) Phase lag index: assessment of functional connectivity from multi channel EEG and MEG with diminished bias from common sources. Hum. Brain Mapp., 28, 1178-1193. Binkofski, F., Schnitzler, A., Enck, P., Frieling, T., Posse, S., Seitz, R.J. & Freund, H.J. (1998) Somatic and limbic cortex activation in esophageal distention: a functional magnetic resonance imaging study. Ann. Neurol., 44, 811-815. Craig, A.D., Chen, K., Bandy, D. & Reiman, E.M. (2000) Thermosensory activation of insular cortex. Nat. Neurosci., 3, 184-190. Cannon, W.B. (1935) Stresses and strains of homeostasis. Am. J. Med. Sci., 189, 13-14. Picard, N. & Strick, P.L. (1996) Motor areas of the medial wall: a review of their location and functional activation. Cereb. Cortex, 6, 342-353. Hilty, L., Lutz, K., Maurer, K., Rodenkirch, T., Spengler, C.M., Boutellier, U., Jancke, L. & Amann, M. (2011) Spinal opioid receptor-sensitive muscle afferents contribute to the fatigue-induced increase in intracortical inhibition in healthy humans. Exp. Physiol., 96, 505-517. Craig, A.D., Bushnell, M.C., Zhang, E.T. & Blomqvist, A. (1994) A thalamic nucleus specific for pain and temperature sensation. Nature, 372, 770-773. Noakes, T.D., St Clair Gibson, A. & Lambert, E.V. (2005) From catastrophe to complexity: a novel model of integrative central neural regulation of effort and fatigue during exercise in humans: summary and conclusions. Br. J. Sports Med., 39, 120-124. Florian, G., Andrew, C. & Pfurtscheller, G. (1998) Do changes in coherence always reflect changes in functional coupling? Electroencephalogr. Clin. Neurophysiol., 106, 87-91. Casey, K.L. (1999) Forebrain mechanisms of nociception and pain: analysis through imaging. Proc. Natl. Acad. Sci. USA, 96, 7668-7674. Hilty, L., Jancke, L., Luechinger, R., Boutellier, U. & Lutz, K. (2010) Limitation of physical performance in a muscle fatiguing handgrip exercise is mediated by thalamo-insular activity. Hum. Brain Mapp., doi: 10.1002/hbm.21177 [Epub ahead of print]. Craig, A.D. (2003b) A new view of pain as a homeostatic emotion. Trends Neurosci., 26, 303-307. Fuchs, M., Kastner, J., Wagner, M., Hawes, S. & Ebersole, J.S. (2002) A standardized boundary element method volume conductor model. Clin. Neurophysiol., 113, 702-712. McClure, S.M., Laibson, D.I., Loewenstein, G. & Cohen, J.D. (2004) Separate neural systems value immediate and delayed monetary rewards. Science, 306, 503-507. Liu, J.Z., Dai, T.H., Sahgal, V., Brown, R.W. & Yue, G.H. (2002) Nonlinear cortical modulation of muscle fatigue: a functional MRI study. Brain Res., 957, 320-329. Nybo, L. & Nielsen, B. (2001) Perceived exertion is associated with an altered brain activity during exercise with progressive hyperthermia. J. Appl. Physiol., 91, 2017-2023. Pfurtscheller, G., Neuper, C. & Krausz, G. (2000) Functional dissociation of lower and upper frequency mu rhythms in relation to voluntary limb movement. Clin. Neurophysiol., 111, 1873-1879. Schneider, S., Brummer, V., Abel, T., Askew, C.D. & Struder, H.K. (2009) Changes in brain cortical activity measured by EEG are related to individual exercise preferences. Physiol. Behav., 98, 447-452. Fitts, R.H. & Holloszy, J.O. (1976) Lactate and contractile force in frog muscle during development of fatigue and recovery. Am. J. Physiol., 231, 430-433. Laibson, D. (1997) Golden eggs and hyperbolic discounting. Quart. J. Econ., 112, 443-478. Brannan, S., Liotti, M., Egan, G., Shade, R., Madden, L., Robillard, R., Abplanalp, B., Stofer, K., Denton, D. & Fox, P.T. (2001) Neuroimaging of cerebral activations and deactivations associated with hypercapnia and hunger for air. Proc. Natl. Acad. Sci. USA, 98, 2029-2034. Liu, J.Z., Shan, Z.Y., Zhang, L.D., Sahgal, V., Brown, R.W. & Yue, G.H. (2003) Human brain activation during sustained and intermittent submaximal fatigue muscle contractions: an FMRI study. J. Neurophysiol., 90, 300-312. Taylor, J.L., Petersen, N., Butler, J.E. & Gandevia, S.C. (2000) Ischaemia after exercise does not reduce responses of human motoneurones to cortical or corticospinal tract stimulation. J. Physiol., 525, 793-801. Laufs, H., Kleinschmidt, A., Beyerle, A., Eger, E., Salek-Haddadi, A., Preibisch, C. & Krakow, K. (2003) EEG-correlated fMRI of human alpha activity. Neuroimage, 19, 1463-1476. Porter, L.L. & Sakamoto, K. (1988) Organization and synaptic relationships of the projection from the primary sensory to the primary motor cortex in the cat. J. Comp. Neurol., 271, 387-396. Davidson, R.J. (1988) EEG measures of cerebral asymmetry: conceptual and methodological issues. Int. J. Neurosci., 39, 71-89. Nolte, G., Bai, O., Wheaton, L., Mari, Z., Vorbach, S. & Hallett, M. (2004) Identifying true brain interaction from EEG data using the imaginary part of coherency. Clin. Neurophysiol., 115, 2292-2307. Baciu, M.V., Bonaz, B.L., Papillon, E., Bost, R.A., Le Bas, J.F., Fournet, J. & Segebarth, C.M. (1999) Central processing of rectal pain: a functional MR imaging study. Am. J. Neuroradiol., 20, 1920-1924. Seymour, B., O'Doherty, J.P., Koltzenburg, M., Wiech, K., Frackowiak, R., Friston, K. & Dolan, R. (2005) Opponent appetitive-aversive neural processes underlie predictive learning of pain relief. Nat. Neurosci., 8, 1234-1240. Gandevia, S.C., Allen, G.M., Butler, J.E. & Taylor, J.L. (1996) Supraspinal factors in human muscle fatigue: evidence for suboptimal output from the motor cortex. J. Physiol., 490, 529-536. Liotti, M., Brannan, S., Egan, G., Shade, R., Madden, L., Abplanalp, B., Robillard, R., Lancaster, J., Zamarripa, F.E., Fox, P.T. & Denton, D. (2001) Brain responses associated with consciousness of breathlessness (air hunger). Proc. Natl. Acad. Sci. USA, 98, 2035-2040. Kupers, R.C., Svensson, P. & Jensen, T.S. (2004) Central representation of muscle pain and mechanical hyperesthesia in the orofacial region: a positron emission tomography study. Pain, 108, 284-293. Martin, P.G., Weerakkody, N., Gandevia, S.C. & Taylor, J.L. (2008) Group III and IV muscle afferents differentially affect the motor cortex and motoneurones in humans. J. Physiol., 586, 1277-1289. St Clair Gibson, A. & Noakes, T.D. (2004) Evidence for complex system integration and dynamic neural regulation of skeletal muscle recruitment during exercise in humans. Br. J. Sports Med., 38, 797-806. Nielsen, B., Hyldig, T., Bidstrup, F., Gonzalez-Alonso, J. & Christoffersen, G.R. (2001) Brain activity and fatigue during prolonged exercise in the heat. Pflugers Arch., 442, 41-48. O'Donnell, R.D., Berkhout, J. & Adey, W.R. (1974) Contamination of scalp EEG spectrum during contraction of cranio-facial muscles. Electroencephalogr. Clin. Neurophysiol., 37, 145-151. Schreurs, K.M., de Ridder, D.T. & Bensing, J.M. (2002) Fatigue in multiple sclerosis: reciprocal relationships with physical disabilities and depression. J. Psychosom. Res., 53, 775-781. Kohler, G. & Boutellier, U. (2005) The generalized force-velocity relationship explains why the preferred pedaling rate of cyclists exceeds the most efficient one. Eur. J. Appl. Physiol., 94, 188-195. Tataranni, P.A., Gautier, J.F., Chen, K., Uecker, A., Bandy, D., Salbe, A.D., Pratley, R.E., Lawson, M., Reiman, 2001; 91 2006; 31 1988; 271 2004; 29 2002; 53 2000; 3 1994; 372 2002; 113 1988; 39 1997; 112 1975 2011; 96 2002; 957 1983; 50 2003; 19 2008; 586 1935; 189 2007; 34 1998; 44 2011; 369 2007; 28 1976; 231 2003; 90 2009; 98 2004; 38 1997; 58 2000; 525 2002; 87 2002; 88 1999; 13 1996; 490 2006; 120 1999; 96 2001; 16 2005; 39 2010; 30 1996; 6 2001; 98 1974; 37 2003b; 26 2001; 442 2010 1998 1999; 20 1993 2000; 111 2009; 1261 2004; 108 2004; 306 2010; 41 2003a; 13 2004; 115 2007b 2007a 2002; 24 2005; 8 1998; 106 2005; 94 2009; 106 e_1_2_8_28_1 e_1_2_8_24_1 e_1_2_8_47_1 e_1_2_8_26_1 e_1_2_8_49_1 e_1_2_8_3_1 Baciu M.V. (e_1_2_8_2_1) 1999; 20 Borg G. (e_1_2_8_5_1) 1975 e_1_2_8_7_1 e_1_2_8_9_1 e_1_2_8_20_1 e_1_2_8_22_1 e_1_2_8_45_1 e_1_2_8_64_1 e_1_2_8_62_1 e_1_2_8_41_1 e_1_2_8_60_1 e_1_2_8_17_1 e_1_2_8_19_1 e_1_2_8_13_1 e_1_2_8_36_1 e_1_2_8_59_1 e_1_2_8_15_1 e_1_2_8_38_1 e_1_2_8_57_1 e_1_2_8_32_1 e_1_2_8_55_1 e_1_2_8_11_1 e_1_2_8_34_1 e_1_2_8_51_1 e_1_2_8_30_1 e_1_2_8_29_1 e_1_2_8_25_1 e_1_2_8_46_1 e_1_2_8_27_1 e_1_2_8_48_1 e_1_2_8_4_1 e_1_2_8_6_1 Pascual‐Marqui R.D. (e_1_2_8_43_1) 2002; 24 e_1_2_8_8_1 e_1_2_8_21_1 e_1_2_8_42_1 e_1_2_8_44_1 e_1_2_8_65_1 e_1_2_8_63_1 e_1_2_8_40_1 e_1_2_8_61_1 e_1_2_8_18_1 Hilty L. (e_1_2_8_23_1) 2010 e_1_2_8_39_1 e_1_2_8_14_1 e_1_2_8_35_1 e_1_2_8_16_1 e_1_2_8_37_1 e_1_2_8_58_1 Reiman E.M. (e_1_2_8_53_1) 1997; 58 e_1_2_8_10_1 e_1_2_8_31_1 e_1_2_8_56_1 e_1_2_8_12_1 e_1_2_8_33_1 e_1_2_8_54_1 e_1_2_8_52_1 e_1_2_8_50_1
References_xml	– reference: Porter, L.L. & Sakamoto, K. (1988) Organization and synaptic relationships of the projection from the primary sensory to the primary motor cortex in the cat. J. Comp. Neurol., 271, 387-396. – reference: Schreurs, K.M., de Ridder, D.T. & Bensing, J.M. (2002) Fatigue in multiple sclerosis: reciprocal relationships with physical disabilities and depression. J. Psychosom. Res., 53, 775-781. – reference: Pascual-Marqui, R.D., Lehmann, D., Koukkou, M., Kochi, K., Anderer, P., Saletu, B., Tanaka, H., Hirata, K., John, E.R., Prichep, L., Biscay-Lirio, R. & Kinoshita, T. (2011) Assessing interactions in the brain with exact low resolution electromagnetic tomography (eLORETA). Philos. Trans. R. Soc. Lond. A, 369, 3768-3784. – reference: Tataranni, P.A., Gautier, J.F., Chen, K., Uecker, A., Bandy, D., Salbe, A.D., Pratley, R.E., Lawson, M., Reiman, E.M. & Ravussin, E. (1999) Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography. Proc. Natl. Acad. Sci. USA, 96, 4569-4574. – reference: Fuchs, M., Kastner, J., Wagner, M., Hawes, S. & Ebersole, J.S. (2002) A standardized boundary element method volume conductor model. Clin. Neurophysiol., 113, 702-712. – reference: Evans, K.C., Banzett, R.B., Adams, L., McKay, L., Frackowiak, R.S. & Corfield, D.R. (2002) BOLD fMRI identifies limbic, paralimbic, and cerebellar activation during air hunger. J. Neurophysiol., 88, 1500-1511. – reference: Casey, K.L. (1999) Forebrain mechanisms of nociception and pain: analysis through imaging. Proc. Natl. Acad. Sci. USA, 96, 7668-7674. – reference: Craig, A.D., Chen, K., Bandy, D. & Reiman, E.M. (2000) Thermosensory activation of insular cortex. Nat. Neurosci., 3, 184-190. – reference: Lou, J.S., Kearns, G., Oken, B., Sexton, G. & Nutt, J. (2001) Exacerbated physical fatigue and mental fatigue in Parkinson's disease. Mov. Disord., 16, 190-196. – reference: Jurcak, V., Tsuzuki, D. & Dan, I. (2007) 10/20, 10/10, and 10/5 systems revisited: their validity as relative head-surface-based positioning systems. Neuroimage, 34, 1600-1611. – reference: Taylor, J.L., Petersen, N., Butler, J.E. & Gandevia, S.C. (2000) Ischaemia after exercise does not reduce responses of human motoneurones to cortical or corticospinal tract stimulation. J. Physiol., 525, 793-801. – reference: Fitts, R.H. & Holloszy, J.O. (1976) Lactate and contractile force in frog muscle during development of fatigue and recovery. Am. J. Physiol., 231, 430-433. – reference: Henderson, L.A., Bandler, R., Gandevia, S.C. & Macefield, V.G. (2006) Distinct forebrain activity patterns during deep versus superficial pain. Pain, 120, 286-296. – reference: Hilty, L., Lutz, K., Maurer, K., Rodenkirch, T., Spengler, C.M., Boutellier, U., Jancke, L. & Amann, M. (2011) Spinal opioid receptor-sensitive muscle afferents contribute to the fatigue-induced increase in intracortical inhibition in healthy humans. Exp. Physiol., 96, 505-517. – reference: Rasmussen, P., Stie, H., Nybo, L. & Nielsen, B. (2004) Heat induced fatigue and changes of the EEG is not related to reduced perfusion of the brain during prolonged exercise in humans. J. Therm. Biol., 29, 731-737. – reference: Cannon, W.B. (1935) Stresses and strains of homeostasis. Am. J. Med. Sci., 189, 13-14. – reference: Nolte, G., Bai, O., Wheaton, L., Mari, Z., Vorbach, S. & Hallett, M. (2004) Identifying true brain interaction from EEG data using the imaginary part of coherency. Clin. Neurophysiol., 115, 2292-2307. – reference: Tajima, S., Yamamoto, S., Tanaka, M., Kataoka, Y., Iwase, M., Yoshikawa, E., Okada, H., Onoe, H., Tsukada, H., Kuratsune, H., Ouchi, Y. & Watanabe, Y. (2010) Medial orbitofrontal cortex is associated with fatigue sensation. Neurol. Res. Int., doi: 10.1155/2010/671421 [Epub ahead of print]. – reference: Davidson, R.J. (1988) EEG measures of cerebral asymmetry: conceptual and methodological issues. Int. J. Neurosci., 39, 71-89. – reference: St Clair Gibson, A. & Noakes, T.D. (2004) Evidence for complex system integration and dynamic neural regulation of skeletal muscle recruitment during exercise in humans. Br. J. Sports Med., 38, 797-806. – reference: Nielsen, B., Hyldig, T., Bidstrup, F., Gonzalez-Alonso, J. & Christoffersen, G.R. (2001) Brain activity and fatigue during prolonged exercise in the heat. Pflugers Arch., 442, 41-48. – reference: Brannan, S., Liotti, M., Egan, G., Shade, R., Madden, L., Robillard, R., Abplanalp, B., Stofer, K., Denton, D. & Fox, P.T. (2001) Neuroimaging of cerebral activations and deactivations associated with hypercapnia and hunger for air. Proc. Natl. Acad. Sci. USA, 98, 2029-2034. – reference: Noakes, T.D., St Clair Gibson, A. & Lambert, E.V. (2005) From catastrophe to complexity: a novel model of integrative central neural regulation of effort and fatigue during exercise in humans: summary and conclusions. Br. J. Sports Med., 39, 120-124. – reference: Liu, J.Z., Shan, Z.Y., Zhang, L.D., Sahgal, V., Brown, R.W. & Yue, G.H. (2003) Human brain activation during sustained and intermittent submaximal fatigue muscle contractions: an FMRI study. J. Neurophysiol., 90, 300-312. – reference: Martin, P.G., Weerakkody, N., Gandevia, S.C. & Taylor, J.L. (2008) Group III and IV muscle afferents differentially affect the motor cortex and motoneurones in humans. J. Physiol., 586, 1277-1289. – reference: Pfurtscheller, G., Brunner, C., Schlogl, A. & Lopes da Silva, F.H. (2006) Mu rhythm (de)synchronization and EEG single-trial classification of different motor imagery tasks. Neuroimage, 31, 153-159. – reference: Sellitto, M., Ciaramelli, E. & di Pellegrino, G. (2010) Myopic discounting of future rewards after medial orbitofrontal damage in humans. J. Neurosci., 30, 16429-16436. – reference: Hilty, L., Jancke, L., Luechinger, R., Boutellier, U. & Lutz, K. (2010) Limitation of physical performance in a muscle fatiguing handgrip exercise is mediated by thalamo-insular activity. Hum. Brain Mapp., doi: 10.1002/hbm.21177 [Epub ahead of print]. – reference: Laibson, D. (1997) Golden eggs and hyperbolic discounting. Quart. J. Econ., 112, 443-478. – reference: Flynn, F.G., Benson, D.F. & Ardila, A. (1999) Anatomy of the insula - functional and clinical correlates. Aphasiology, 13, 55-78. – reference: Craig, A.D. (2003b) A new view of pain as a homeostatic emotion. Trends Neurosci., 26, 303-307. – reference: Taylor, J.L., Butler, J.E., Allen, G.M. & Gandevia, S.C. (1996) Changes in motor cortical excitability during human muscle fatigue. J. Physiol., 490, 519-528. – reference: Rauch, H.G., St Clair Gibson, A., Lambert, E.V. & Noakes, T.D. (2005) A signalling role for muscle glycogen in the regulation of pace during prolonged exercise. Br. J. Sports Med., 39, 34-38. – reference: Ftaiti, F., Kacem, A., Jaidane, N., Tabka, Z. & Dogui, M. (2010) Changes in EEG activity before and after exhaustive exercise in sedentary women in neutral and hot environments. Appl. Ergon., 41, 806-811. – reference: Binkofski, F., Schnitzler, A., Enck, P., Frieling, T., Posse, S., Seitz, R.J. & Freund, H.J. (1998) Somatic and limbic cortex activation in esophageal distention: a functional magnetic resonance imaging study. Ann. Neurol., 44, 811-815. – reference: Reiman, E.M. (1997) The application of positron emission tomography to the study of normal and pathologic emotions. J. Clin. Psychiatry, 58(Suppl 16), 4-12. – reference: McClure, S.M., Laibson, D.I., Loewenstein, G. & Cohen, J.D. (2004) Separate neural systems value immediate and delayed monetary rewards. Science, 306, 503-507. – reference: O'Donnell, R.D., Berkhout, J. & Adey, W.R. (1974) Contamination of scalp EEG spectrum during contraction of cranio-facial muscles. Electroencephalogr. Clin. Neurophysiol., 37, 145-151. – reference: Seymour, B., O'Doherty, J.P., Koltzenburg, M., Wiech, K., Frackowiak, R., Friston, K. & Dolan, R. (2005) Opponent appetitive-aversive neural processes underlie predictive learning of pain relief. Nat. Neurosci., 8, 1234-1240. – reference: Nybo, L. & Nielsen, B. (2001) Perceived exertion is associated with an altered brain activity during exercise with progressive hyperthermia. J. Appl. Physiol., 91, 2017-2023. – reference: Stam, C.J., Nolte, G. & Daffertshofer, A. (2007) Phase lag index: assessment of functional connectivity from multi channel EEG and MEG with diminished bias from common sources. Hum. Brain Mapp., 28, 1178-1193. – reference: Craig, A.D. (2003a) Interoception: the sense of the physiological condition of the body. Curr. Opin. Neurobiol., 13, 500-505. – reference: Kohler, G. & Boutellier, U. (2005) The generalized force-velocity relationship explains why the preferred pedaling rate of cyclists exceeds the most efficient one. Eur. J. Appl. Physiol., 94, 188-195. – reference: Gandevia, S.C., Allen, G.M., Butler, J.E. & Taylor, J.L. (1996) Supraspinal factors in human muscle fatigue: evidence for suboptimal output from the motor cortex. J. Physiol., 490, 529-536. – reference: Craig, A.D., Bushnell, M.C., Zhang, E.T. & Blomqvist, A. (1994) A thalamic nucleus specific for pain and temperature sensation. Nature, 372, 770-773. – reference: Liu, J.Z., Dai, T.H., Sahgal, V., Brown, R.W. & Yue, G.H. (2002) Nonlinear cortical modulation of muscle fatigue: a functional MRI study. Brain Res., 957, 320-329. – reference: Wilson, L.B., Andrew, D. & Craig, A.D. (2002) Activation of spinobulbar lamina I neurons by static muscle contraction. J. Neurophysiol., 87, 1641-1645. – reference: Florian, G., Andrew, C. & Pfurtscheller, G. (1998) Do changes in coherence always reflect changes in functional coupling? Electroencephalogr. Clin. Neurophysiol., 106, 87-91. – reference: Kupers, R.C., Svensson, P. & Jensen, T.S. (2004) Central representation of muscle pain and mechanical hyperesthesia in the orofacial region: a positron emission tomography study. Pain, 108, 284-293. – reference: Pfurtscheller, G., Neuper, C. & Krausz, G. (2000) Functional dissociation of lower and upper frequency mu rhythms in relation to voluntary limb movement. Clin. Neurophysiol., 111, 1873-1879. – reference: Laufs, H., Kleinschmidt, A., Beyerle, A., Eger, E., Salek-Haddadi, A., Preibisch, C. & Krakow, K. (2003) EEG-correlated fMRI of human alpha activity. Neuroimage, 19, 1463-1476. – reference: Picard, N. & Strick, P.L. (1996) Motor areas of the medial wall: a review of their location and functional activation. Cereb. Cortex, 6, 342-353. – reference: Marcora, S.M., Staiano, W. & Manning, V. (2009) Mental fatigue impairs physical performance in humans. J. Appl. Physiol., 106, 857-864. – reference: Xu, L., Liang, Z.Y., Wang, K., Li, S. & Jiang, T. (2009) Neural mechanism of intertemporal choice: from discounting future gains to future losses. Brain Res., 1261, 65-74. – reference: Bigland-Ritchie, B., Johansson, R., Lippold, O.C. & Woods, J.J. (1983) Contractile speed and EMG changes during fatigue of sustained maximal voluntary contractions. J. Neurophysiol., 50, 313-324. – reference: Liotti, M., Brannan, S., Egan, G., Shade, R., Madden, L., Abplanalp, B., Robillard, R., Lancaster, J., Zamarripa, F.E., Fox, P.T. & Denton, D. (2001) Brain responses associated with consciousness of breathlessness (air hunger). Proc. Natl. Acad. Sci. USA, 98, 2035-2040. – reference: Pascual-Marqui, R.D. (2002) Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. Methods Find. Exp. Clin. Pharmacol., 24(Suppl D), 5-12. – reference: Schneider, S., Brummer, V., Abel, T., Askew, C.D. & Struder, H.K. (2009) Changes in brain cortical activity measured by EEG are related to individual exercise preferences. Physiol. Behav., 98, 447-452. – reference: Baciu, M.V., Bonaz, B.L., Papillon, E., Bost, R.A., Le Bas, J.F., Fournet, J. & Segebarth, C.M. (1999) Central processing of rectal pain: a functional MR imaging study. Am. J. Neuroradiol., 20, 1920-1924. – volume: 113 start-page: 702 year: 2002 end-page: 712 article-title: A standardized boundary element method volume conductor model publication-title: Clin. Neurophysiol. – volume: 91 start-page: 2017 year: 2001 end-page: 2023 article-title: Perceived exertion is associated with an altered brain activity during exercise with progressive hyperthermia publication-title: J. Appl. Physiol. – volume: 115 start-page: 2292 year: 2004 end-page: 2307 article-title: Identifying true brain interaction from EEG data using the imaginary part of coherency publication-title: Clin. Neurophysiol. – volume: 16 start-page: 190 year: 2001 end-page: 196 article-title: Exacerbated physical fatigue and mental fatigue in Parkinson’s disease publication-title: Mov. Disord. – year: 2007b – volume: 96 start-page: 505 year: 2011 end-page: 517 article-title: Spinal opioid receptor‐sensitive muscle afferents contribute to the fatigue‐induced increase in intracortical inhibition in healthy humans publication-title: Exp. Physiol. – volume: 39 start-page: 120 year: 2005 end-page: 124 article-title: From catastrophe to complexity: a novel model of integrative central neural regulation of effort and fatigue during exercise in humans: summary and conclusions publication-title: Br. J. Sports Med. – volume: 490 start-page: 529 year: 1996 end-page: 536 article-title: Supraspinal factors in human muscle fatigue: evidence for suboptimal output from the motor cortex publication-title: J. Physiol. – volume: 98 start-page: 447 year: 2009 end-page: 452 article-title: Changes in brain cortical activity measured by EEG are related to individual exercise preferences publication-title: Physiol. Behav. – volume: 369 start-page: 3768 year: 2011 end-page: 3784 article-title: Assessing interactions in the brain with exact low resolution electromagnetic tomography (eLORETA) publication-title: Philos. Trans. R. Soc. Lond. A – volume: 20 start-page: 1920 year: 1999 end-page: 1924 article-title: Central processing of rectal pain: a functional MR imaging study publication-title: Am. J. Neuroradiol. – volume: 98 start-page: 2035 year: 2001 end-page: 2040 article-title: Brain responses associated with consciousness of breathlessness (air hunger) publication-title: Proc. Natl. Acad. Sci. USA – volume: 26 start-page: 303 year: 2003b end-page: 307 article-title: A new view of pain as a homeostatic emotion publication-title: Trends Neurosci. – volume: 106 start-page: 87 year: 1998 end-page: 91 article-title: Do changes in coherence always reflect changes in functional coupling? publication-title: Electroencephalogr. Clin. Neurophysiol. – start-page: 189 year: 1998 end-page: 197 – volume: 58 start-page: 4 issue: Suppl 16 year: 1997 end-page: 12 article-title: The application of positron emission tomography to the study of normal and pathologic emotions publication-title: J. Clin. Psychiatry – volume: 8 start-page: 1234 year: 2005 end-page: 1240 article-title: Opponent appetitive‐aversive neural processes underlie predictive learning of pain relief publication-title: Nat. Neurosci. – volume: 306 start-page: 503 year: 2004 end-page: 507 article-title: Separate neural systems value immediate and delayed monetary rewards publication-title: Science – volume: 13 start-page: 55 year: 1999 end-page: 78 article-title: Anatomy of the insula – functional and clinical correlates publication-title: Aphasiology – volume: 30 start-page: 16429 year: 2010 end-page: 16436 article-title: Myopic discounting of future rewards after medial orbitofrontal damage in humans publication-title: J. Neurosci. – volume: 39 start-page: 71 year: 1988 end-page: 89 article-title: EEG measures of cerebral asymmetry: conceptual and methodological issues publication-title: Int. J. Neurosci. – volume: 41 start-page: 806 year: 2010 end-page: 811 article-title: Changes in EEG activity before and after exhaustive exercise in sedentary women in neutral and hot environments publication-title: Appl. Ergon. – volume: 112 start-page: 443 year: 1997 end-page: 478 article-title: Golden eggs and hyperbolic discounting publication-title: Quart. J. Econ. – volume: 957 start-page: 320 year: 2002 end-page: 329 article-title: Nonlinear cortical modulation of muscle fatigue: a functional MRI study publication-title: Brain Res. – volume: 37 start-page: 145 year: 1974 end-page: 151 article-title: Contamination of scalp EEG spectrum during contraction of cranio‐facial muscles publication-title: Electroencephalogr. Clin. Neurophysiol. – start-page: 39 year: 1975 end-page: 46 – volume: 19 start-page: 1463 year: 2003 end-page: 1476 article-title: EEG‐correlated fMRI of human alpha activity publication-title: Neuroimage – volume: 44 start-page: 811 year: 1998 end-page: 815 article-title: Somatic and limbic cortex activation in esophageal distention: a functional magnetic resonance imaging study publication-title: Ann. Neurol. – volume: 6 start-page: 342 year: 1996 end-page: 353 article-title: Motor areas of the medial wall: a review of their location and functional activation publication-title: Cereb. Cortex – volume: 271 start-page: 387 year: 1988 end-page: 396 article-title: Organization and synaptic relationships of the projection from the primary sensory to the primary motor cortex in the cat publication-title: J. Comp. Neurol. – year: 1993 – volume: 586 start-page: 1277 year: 2008 end-page: 1289 article-title: Group III and IV muscle afferents differentially affect the motor cortex and motoneurones in humans publication-title: J. Physiol. – volume: 13 start-page: 500 year: 2003a end-page: 505 article-title: Interoception: the sense of the physiological condition of the body publication-title: Curr. Opin. Neurobiol. – volume: 24 start-page: 5 issue: Suppl D year: 2002 end-page: 12 article-title: Standardized low‐resolution brain electromagnetic tomography (sLORETA): technical details publication-title: Methods Find. Exp. Clin. Pharmacol. – volume: 87 start-page: 1641 year: 2002 end-page: 1645 article-title: Activation of spinobulbar lamina I neurons by static muscle contraction publication-title: J. Neurophysiol. – volume: 29 start-page: 731 year: 2004 end-page: 737 article-title: Heat induced fatigue and changes of the EEG is not related to reduced perfusion of the brain during prolonged exercise in humans publication-title: J. Therm. Biol. – volume: 372 start-page: 770 year: 1994 end-page: 773 article-title: A thalamic nucleus specific for pain and temperature sensation publication-title: Nature – volume: 98 start-page: 2029 year: 2001 end-page: 2034 article-title: Neuroimaging of cerebral activations and deactivations associated with hypercapnia and hunger for air publication-title: Proc. Natl. Acad. Sci. USA – volume: 31 start-page: 153 year: 2006 end-page: 159 article-title: Mu rhythm (de)synchronization and EEG single‐trial classification of different motor imagery tasks publication-title: Neuroimage – volume: 90 start-page: 300 year: 2003 end-page: 312 article-title: Human brain activation during sustained and intermittent submaximal fatigue muscle contractions: an FMRI study publication-title: J. Neurophysiol. – volume: 120 start-page: 286 year: 2006 end-page: 296 article-title: Distinct forebrain activity patterns during deep versus superficial pain publication-title: Pain – volume: 108 start-page: 284 year: 2004 end-page: 293 article-title: Central representation of muscle pain and mechanical hyperesthesia in the orofacial region: a positron emission tomography study publication-title: Pain – volume: 53 start-page: 775 year: 2002 end-page: 781 article-title: Fatigue in multiple sclerosis: reciprocal relationships with physical disabilities and depression publication-title: J. Psychosom. Res. – volume: 38 start-page: 797 year: 2004 end-page: 806 article-title: Evidence for complex system integration and dynamic neural regulation of skeletal muscle recruitment during exercise in humans publication-title: Br. J. Sports Med. – volume: 34 start-page: 1600 year: 2007 end-page: 1611 article-title: 10/20, 10/10, and 10/5 systems revisited: their validity as relative head‐surface‐based positioning systems publication-title: Neuroimage – volume: 231 start-page: 430 year: 1976 end-page: 433 article-title: Lactate and contractile force in frog muscle during development of fatigue and recovery publication-title: Am. J. Physiol. – volume: 39 start-page: 34 year: 2005 end-page: 38 article-title: A signalling role for muscle glycogen in the regulation of pace during prolonged exercise publication-title: Br. J. Sports Med. – volume: 111 start-page: 1873 year: 2000 end-page: 1879 article-title: Functional dissociation of lower and upper frequency mu rhythms in relation to voluntary limb movement publication-title: Clin. Neurophysiol. – volume: 3 start-page: 184 year: 2000 end-page: 190 article-title: Thermosensory activation of insular cortex publication-title: Nat. Neurosci. – volume: 94 start-page: 188 year: 2005 end-page: 195 article-title: The generalized force‐velocity relationship explains why the preferred pedaling rate of cyclists exceeds the most efficient one publication-title: Eur. J. Appl. Physiol. – volume: 525 start-page: 793 year: 2000 end-page: 801 article-title: Ischaemia after exercise does not reduce responses of human motoneurones to cortical or corticospinal tract stimulation publication-title: J. Physiol. – volume: 50 start-page: 313 year: 1983 end-page: 324 article-title: Contractile speed and EMG changes during fatigue of sustained maximal voluntary contractions publication-title: J. Neurophysiol. – year: 2010 article-title: Medial orbitofrontal cortex is associated with fatigue sensation publication-title: Neurol. Res. Int. – volume: 88 start-page: 1500 year: 2002 end-page: 1511 article-title: BOLD fMRI identifies limbic, paralimbic, and cerebellar activation during air hunger publication-title: J. Neurophysiol. – year: 2007a – year: 2010 article-title: Limitation of physical performance in a muscle fatiguing handgrip exercise is mediated by thalamo‐insular activity publication-title: Hum. Brain Mapp. – volume: 490 start-page: 519 year: 1996 end-page: 528 article-title: Changes in motor cortical excitability during human muscle fatigue publication-title: J. Physiol. – volume: 189 start-page: 13 year: 1935 end-page: 14 article-title: Stresses and strains of homeostasis publication-title: Am. J. Med. Sci. – volume: 28 start-page: 1178 year: 2007 end-page: 1193 article-title: Phase lag index: assessment of functional connectivity from multi channel EEG and MEG with diminished bias from common sources publication-title: Hum. Brain Mapp. – volume: 442 start-page: 41 year: 2001 end-page: 48 article-title: Brain activity and fatigue during prolonged exercise in the heat publication-title: Pflugers Arch. – volume: 96 start-page: 7668 year: 1999 end-page: 7674 article-title: Forebrain mechanisms of nociception and pain: analysis through imaging publication-title: Proc. Natl. Acad. Sci. USA – volume: 106 start-page: 857 year: 2009 end-page: 864 article-title: Mental fatigue impairs physical performance in humans publication-title: J. Appl. Physiol. – volume: 1261 start-page: 65 year: 2009 end-page: 74 article-title: Neural mechanism of intertemporal choice: from discounting future gains to future losses publication-title: Brain Res. – volume: 96 start-page: 4569 year: 1999 end-page: 4574 article-title: Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography publication-title: Proc. Natl. Acad. Sci. USA – ident: e_1_2_8_16_1 doi: 10.1152/ajplegacy.1976.231.2.430 – ident: e_1_2_8_47_1 doi: 10.1016/S1388-2457(00)00428-4 – ident: e_1_2_8_45_1 – ident: e_1_2_8_65_1 doi: 10.1016/j.brainres.2008.12.061 – ident: e_1_2_8_28_1 doi: 10.1016/j.pain.2003.12.029 – ident: e_1_2_8_38_1 doi: 10.1007/s004240100515 – ident: e_1_2_8_39_1 doi: 10.1136/bjsm.2003.010330 – volume: 58 start-page: 4 issue: 16 year: 1997 ident: e_1_2_8_53_1 article-title: The application of positron emission tomography to the study of normal and pathologic emotions publication-title: J. Clin. Psychiatry – ident: e_1_2_8_15_1 doi: 10.1152/jn.2002.88.3.1500 – ident: e_1_2_8_44_1 – ident: e_1_2_8_12_1 doi: 10.1038/72131 – ident: e_1_2_8_41_1 doi: 10.1152/jappl.2001.91.5.2017 – ident: e_1_2_8_42_1 doi: 10.1016/0013-4694(74)90005-4 – ident: e_1_2_8_64_1 doi: 10.1152/jn.00609.2001 – volume: 20 start-page: 1920 year: 1999 ident: e_1_2_8_2_1 article-title: Central processing of rectal pain: a functional MR imaging study publication-title: Am. J. Neuroradiol. – ident: e_1_2_8_62_1 doi: 10.1113/jphysiol.1996.sp021163 – ident: e_1_2_8_58_1 doi: 10.1136/bjsm.2003.009852 – ident: e_1_2_8_46_1 doi: 10.1098/rsta.2011.0081 – ident: e_1_2_8_55_1 doi: 10.1016/S0022-3999(02)00326-4 – year: 2010 ident: e_1_2_8_23_1 article-title: Limitation of physical performance in a muscle fatiguing handgrip exercise is mediated by thalamo‐insular activity publication-title: Hum. Brain Mapp. – ident: e_1_2_8_61_1 doi: 10.1073/pnas.96.8.4569 – ident: e_1_2_8_24_1 doi: 10.1113/expphysiol.2010.056226 – ident: e_1_2_8_60_1 doi: 10.1155/2010/671421 – ident: e_1_2_8_7_1 doi: 10.1097/00000441-193501000-00001 – ident: e_1_2_8_21_1 doi: 10.1113/jphysiol.1996.sp021164 – ident: e_1_2_8_40_1 doi: 10.1016/j.clinph.2004.04.029 – ident: e_1_2_8_56_1 doi: 10.1523/JNEUROSCI.2516-10.2010 – ident: e_1_2_8_6_1 doi: 10.1073/pnas.98.4.2029 – ident: e_1_2_8_13_1 doi: 10.3109/00207458808985694 – ident: e_1_2_8_57_1 doi: 10.1038/nn1527 – ident: e_1_2_8_10_1 doi: 10.1016/S0166-2236(03)00123-1 – ident: e_1_2_8_29_1 doi: 10.1162/003355397555253 – ident: e_1_2_8_3_1 doi: 10.1152/jn.1983.50.1.313 – ident: e_1_2_8_26_1 doi: 10.1016/j.neuroimage.2006.09.024 – ident: e_1_2_8_50_1 doi: 10.1002/cne.902710307 – ident: e_1_2_8_51_1 doi: 10.1016/j.jtherbio.2004.08.047 – ident: e_1_2_8_59_1 doi: 10.1002/hbm.20346 – ident: e_1_2_8_35_1 doi: 10.1152/japplphysiol.91324.2008 – ident: e_1_2_8_27_1 doi: 10.1007/s00421-004-1283-2 – ident: e_1_2_8_20_1 doi: 10.1016/S1388-2457(02)00030-5 – ident: e_1_2_8_4_1 doi: 10.1002/ana.410440516 – ident: e_1_2_8_63_1 doi: 10.1111/j.1469-7793.2000.00793.x – ident: e_1_2_8_11_1 doi: 10.1038/372770a0 – ident: e_1_2_8_18_1 doi: 10.1080/026870399402325 – ident: e_1_2_8_31_1 doi: 10.1073/pnas.98.4.2035 – ident: e_1_2_8_8_1 doi: 10.1073/pnas.96.14.7668 – start-page: 39 volume-title: Physical Work and Effort year: 1975 ident: e_1_2_8_5_1 – ident: e_1_2_8_17_1 doi: 10.1016/S0013-4694(97)00105-3 – ident: e_1_2_8_49_1 doi: 10.1093/cercor/6.3.342 – ident: e_1_2_8_30_1 doi: 10.1016/S1053-8119(03)00286-6 – ident: e_1_2_8_33_1 doi: 10.1152/jn.00821.2002 – ident: e_1_2_8_34_1 doi: 10.1002/mds.1042 – ident: e_1_2_8_25_1 doi: 10.1007/978-1-4615-5351-9_17 – ident: e_1_2_8_9_1 doi: 10.1016/S0959-4388(03)00090-4 – ident: e_1_2_8_14_1 doi: 10.1109/NSSMIC.1993.373602 – ident: e_1_2_8_22_1 doi: 10.1016/j.pain.2005.11.003 – volume: 24 start-page: 5 year: 2002 ident: e_1_2_8_43_1 article-title: Standardized low‐resolution brain electromagnetic tomography (sLORETA): technical details publication-title: Methods Find. Exp. Clin. Pharmacol. – ident: e_1_2_8_32_1 doi: 10.1016/S0006-8993(02)03665-X – ident: e_1_2_8_48_1 doi: 10.1016/j.neuroimage.2005.12.003 – ident: e_1_2_8_54_1 doi: 10.1016/j.physbeh.2009.07.010 – ident: e_1_2_8_37_1 doi: 10.1126/science.1100907 – ident: e_1_2_8_19_1 doi: 10.1016/j.apergo.2010.01.008 – ident: e_1_2_8_36_1 doi: 10.1113/jphysiol.2007.140426 – ident: e_1_2_8_52_1 doi: 10.1136/bjsm.2003.010645
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Snippet	In the present study, intracortical communication between mid/anterior insular and motor cortex was investigated during a fatiguing cycling exercise. From 16...
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SubjectTerms	Adult Cerebral Cortex - anatomy & histology Cerebral Cortex - physiology EEG Electroencephalography exercise Exercise - physiology homeostatic functions Humans lagged phase synchronization Male Motor Cortex - physiology Muscle Fatigue - physiology Nerve Net - anatomy & histology Nerve Net - physiology supraspinal fatigue Young Adult
Title	Fatigue-induced increase in intracortical communication between mid/anterior insular and motor cortex during cycling exercise
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