Clinical translation of ferumoxytol‐based vessel size imaging (VSI): Feasibility in a phase I oncology clinical trial population

Purpose To assess the feasibility of acquiring vessel size imaging (VSI) metrics using ferumoxytol injections and stock pulse sequences in a multicenter Phase I trial of a novel therapy in patients with advanced metastatic disease. Methods Scans were acquired before, immediately after, and 48 h afte...

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Veröffentlicht in:	Magnetic resonance in medicine Jg. 77; H. 2; S. 814 - 825
Hauptverfasser:	Fredrickson, Jill, Serkova, Natalie J., Wyatt, Shelby K., Carano, Richard A.D., Pirzkall, Andrea, Rhee, Ina, Rosen, Lee S., Bessudo, Alberto, Weekes, Colin, de Crespigny, Alex
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 01.02.2017
Schlagworte:	angiogenesis Animals Blood vessels Contrast agents Contrast Media - metabolism DCE‐MRI Feasibility studies Ferrosoferric Oxide - metabolism Humans Image acquisition Image Processing, Computer-Assisted - methods Injection Liver Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical imaging Metastases Mice Mice, Nude Muscles Neoplasms - diagnostic imaging Neoplasms - metabolism Neoplasms, Experimental - diagnostic imaging Neuroimaging Patients tumor Tumors USPIO vessel size VSI Xenografts Xenotransplantation vessel size DCE-MRI USPIO VSI angiogenesis tumor
ISSN:	0740-3194, 1522-2594, 1522-2594
Online-Zugang:	Volltext
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