The role of ventricular–arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases, European Association of Cardiovascular Imaging, and Heart Failure Association

Ventricular–arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment possesses independent diagnostic and prognostic value and may be used to refine riskstratification and monitor therapeutic in...

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Vydáno v:European journal of heart failure Ročník 21; číslo 4; s. 402 - 424
Hlavní autoři: Ikonomidis, Ignatios, Aboyans, Victor, Blacher, Jacque, Brodmann, Marianne, Brutsaert, Dirk L., Chirinos, Julio A., De Carlo, Marco, Delgado, Victoria, Lancellotti, Patrizio, Lekakis, John, Mohty, Dania, Nihoyannopoulos, Petros, Parissis, John, Rizzoni, Damiano, Ruschitzka, Frank, Seferovic, Petar, Stabile, Eugenio, Tousoulis, Dimitrios, Vinereanu, Dragos, Vlachopoulos, Charalambos, Vlastos, Dimitrios, Xaplanteris, Panagiotis, Zimlichman, Reuven, Metra, Marco
Médium: Journal Article
Jazyk:angličtina
Vydáno: Oxford, UK John Wiley & Sons, Ltd 01.04.2019
European Society of Cardiology (Wiley)
Wiley-Blackwell
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ISSN:1388-9842, 1879-0844, 1879-0844
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Abstract Ventricular–arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment possesses independent diagnostic and prognostic value and may be used to refine riskstratification and monitor therapeutic interventions. Traditionally, VAC is assessed by the non‐invasive measurement of the ratio of arterial (Ea) to ventricular end‐systolic elastance (Ees). With disease progression, both Ea and Ees may become abnormal and the Ea/Ees ratio may approximate its normal values. Therefore, the measurement of each component of this ratio or of novel more sensitive markers of myocardial (e.g. global longitudinal strain) and arterial function (e.g. pulse wave velocity) may better characterize VAC. In valvular heart disease, systemic arterial compliance and valvulo–arterial impedance have an established diagnostic and prognostic value and may monitor the effects of valve replacement on vascular and cardiac function. Treatment guided to improve VAC through improvement of both or each one of its components may delay incidence of heart failure and possibly improve prognosis in heart failure. In this consensus document, we describe the pathophysiology, the methods of assessment as well as the clinical implications of VAC in cardiac diseases and heart failure. Finally, we focus on interventions that may improve VAC and thus modify prognosis.
AbstractList Ventricular-arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment possesses independent diagnostic and prognostic value and may be used to refine riskstratification and monitor therapeutic interventions. Traditionally, VAC is assessed by the non-invasive measurement of the ratio of arterial (Ea) to ventricular end-systolic elastance (Ees). With disease progression, both Ea and Ees may become abnormal and the Ea/Ees ratio may approximate its normal values. Therefore, the measurement of each component of this ratio or of novel more sensitive markers of myocardial (e.g. global longitudinal strain) and arterial function (e.g. pulse wave velocity) may better characterize VAC. In valvular heart disease, systemic arterial compliance and valvulo-arterial impedance have an established diagnostic and prognostic value and may monitor the effects of valve replacement on vascular and cardiac function. Treatment guided to improve VAC through improvement of both or each one of its components may delay incidence of heart failure and possibly improve prognosis in heart failure. In this consensus document, we describe the pathophysiology, the methods of assessment as well as the clinical implications of VAC in cardiac diseases and heart failure. Finally, we focus on interventions that may improve VAC and thus modify prognosis.
Ventricular-arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment possesses independent diagnostic and prognostic value and may be used to refine riskstratification and monitor therapeutic interventions. Traditionally, VAC is assessed by the non-invasive measurement of the ratio of arterial (Ea) to ventricular end-systolic elastance (Ees). With disease progression, both Ea and Ees may become abnormal and the Ea/Ees ratio may approximate its normal values. Therefore, the measurement of each component of this ratio or of novel more sensitive markers of myocardial (e.g. global longitudinal strain) and arterial function (e.g. pulse wave velocity) may better characterize VAC. In valvular heart disease, systemic arterial compliance and valvulo-arterial impedance have an established diagnostic and prognostic value and may monitor the effects of valve replacement on vascular and cardiac function. Treatment guided to improve VAC through improvement of both or each one of its components may delay incidence of heart failure and possibly improve prognosis in heart failure. In this consensus document, we describe the pathophysiology, the methods of assessment as well as the clinical implications of VAC in cardiac diseases and heart failure. Finally, we focus on interventions that may improve VAC and thus modify prognosis.Ventricular-arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment possesses independent diagnostic and prognostic value and may be used to refine riskstratification and monitor therapeutic interventions. Traditionally, VAC is assessed by the non-invasive measurement of the ratio of arterial (Ea) to ventricular end-systolic elastance (Ees). With disease progression, both Ea and Ees may become abnormal and the Ea/Ees ratio may approximate its normal values. Therefore, the measurement of each component of this ratio or of novel more sensitive markers of myocardial (e.g. global longitudinal strain) and arterial function (e.g. pulse wave velocity) may better characterize VAC. In valvular heart disease, systemic arterial compliance and valvulo-arterial impedance have an established diagnostic and prognostic value and may monitor the effects of valve replacement on vascular and cardiac function. Treatment guided to improve VAC through improvement of both or each one of its components may delay incidence of heart failure and possibly improve prognosis in heart failure. In this consensus document, we describe the pathophysiology, the methods of assessment as well as the clinical implications of VAC in cardiac diseases and heart failure. Finally, we focus on interventions that may improve VAC and thus modify prognosis.
Author Lekakis, John
Stabile, Eugenio
De Carlo, Marco
Ruschitzka, Frank
Vlastos, Dimitrios
Vinereanu, Dragos
Tousoulis, Dimitrios
Nihoyannopoulos, Petros
Vlachopoulos, Charalambos
Lancellotti, Patrizio
Parissis, John
Brutsaert, Dirk L.
Ikonomidis, Ignatios
Blacher, Jacque
Rizzoni, Damiano
Seferovic, Petar
Delgado, Victoria
Xaplanteris, Panagiotis
Zimlichman, Reuven
Chirinos, Julio A.
Brodmann, Marianne
Aboyans, Victor
Mohty, Dania
Metra, Marco
Author_xml – sequence: 1
  givenname: Ignatios
  surname: Ikonomidis
  fullname: Ikonomidis, Ignatios
  email: ignoik@gmail.com
  organization: Athens University Hospital Attikon, National and Kapodistrian University of Athens, School of Medicine
– sequence: 2
  givenname: Victor
  surname: Aboyans
  fullname: Aboyans, Victor
  organization: Limoges School of Medicine
– sequence: 3
  givenname: Jacque
  surname: Blacher
  fullname: Blacher, Jacque
  organization: Paris‐Descartes University, Hôtel‐Dieu Hospital, AP‐HP
– sequence: 4
  givenname: Marianne
  surname: Brodmann
  fullname: Brodmann, Marianne
  organization: Medical University Graz
– sequence: 5
  givenname: Dirk L.
  surname: Brutsaert
  fullname: Brutsaert, Dirk L.
  organization: University Hospital Antwerp
– sequence: 6
  givenname: Julio A.
  surname: Chirinos
  fullname: Chirinos, Julio A.
  organization: University of Pennsylvania
– sequence: 7
  givenname: Marco
  surname: De Carlo
  fullname: De Carlo, Marco
  organization: Azienda Ospedaliero‐Universitaria Pisana
– sequence: 8
  givenname: Victoria
  surname: Delgado
  fullname: Delgado, Victoria
  organization: Leiden University Medical Centre
– sequence: 9
  givenname: Patrizio
  surname: Lancellotti
  fullname: Lancellotti, Patrizio
  organization: Anthea Hospital
– sequence: 10
  givenname: John
  surname: Lekakis
  fullname: Lekakis, John
  organization: Athens University Hospital Attikon, National and Kapodistrian University of Athens, School of Medicine
– sequence: 11
  givenname: Dania
  surname: Mohty
  fullname: Mohty, Dania
  organization: Limoges School of Medicine
– sequence: 12
  givenname: Petros
  surname: Nihoyannopoulos
  fullname: Nihoyannopoulos, Petros
  organization: National and Kapodistrian University of Athens, Medical School
– sequence: 13
  givenname: John
  surname: Parissis
  fullname: Parissis, John
  organization: National and Kapodistrian University of Athens, Athens University Hospital Attikon
– sequence: 14
  givenname: Damiano
  surname: Rizzoni
  fullname: Rizzoni, Damiano
  organization: University of Brescia
– sequence: 15
  givenname: Frank
  surname: Ruschitzka
  fullname: Ruschitzka, Frank
  organization: University Heart Center
– sequence: 16
  givenname: Petar
  surname: Seferovic
  fullname: Seferovic, Petar
  organization: University of Belgrade
– sequence: 17
  givenname: Eugenio
  surname: Stabile
  fullname: Stabile, Eugenio
  organization: ‘Federico II’ University
– sequence: 18
  givenname: Dimitrios
  surname: Tousoulis
  fullname: Tousoulis, Dimitrios
  organization: National and Kapodistrian University of Athens, Medical School
– sequence: 19
  givenname: Dragos
  surname: Vinereanu
  fullname: Vinereanu, Dragos
  organization: University and Emergency Hospital
– sequence: 20
  givenname: Charalambos
  surname: Vlachopoulos
  fullname: Vlachopoulos, Charalambos
  organization: National and Kapodistrian University of Athens, Medical School
– sequence: 21
  givenname: Dimitrios
  surname: Vlastos
  fullname: Vlastos, Dimitrios
  organization: Athens University Hospital Attikon, National and Kapodistrian University of Athens, School of Medicine
– sequence: 22
  givenname: Panagiotis
  surname: Xaplanteris
  fullname: Xaplanteris, Panagiotis
  organization: National and Kapodistrian University of Athens, Medical School
– sequence: 23
  givenname: Reuven
  surname: Zimlichman
  fullname: Zimlichman, Reuven
  organization: Tel Aviv University
– sequence: 24
  givenname: Marco
  surname: Metra
  fullname: Metra, Marco
  organization: University of Brescia
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30859669$$D View this record in MEDLINE/PubMed
https://unilim.hal.science/hal-02086291$$DView record in HAL
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Issue 4
Keywords Heart failure
Hypertension
Valvular heart disease
Arterial elastance
Prognosis
Treatment
Pulse wave velocity
Global longitudinal strain
Ventricular elastance
Coronary artery disease
Ventricular-arterial coupling
Inflammatory disease
Language English
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Snippet Ventricular–arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease....
Ventricular-arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic mechanics, as well as in the pathophysiology of cardiac disease....
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StartPage 402
SubjectTerms Arterial elastance
Cardiovascular & respiratory systems
Coronary artery disease
Global longitudinal strain
Heart failure
Human health sciences
Hypertension
Inflammatory disease
Life Sciences
Prognosis
Pulse wave velocity
Santé publique et épidémiologie
Sciences de la santé humaine
Systèmes cardiovasculaire & respiratoire
Treatment
Valvular heart disease
Ventricular elastance
Ventricular-arterial coupling
Title The role of ventricular–arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases, European Association of Cardiovascular Imaging, and Heart Failure Association
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fejhf.1436
https://www.ncbi.nlm.nih.gov/pubmed/30859669
https://www.proquest.com/docview/2190484920
https://unilim.hal.science/hal-02086291
https://orbi.uliege.be/handle/2268/241438
Volume 21
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