Mediation analysis of time‐to‐event endpoints accounting for repeatedly measured mediators subject to time‐varying confounding

In this article, we will present statistical methods to assess to what extent the effect of a randomised treatment (versus control) on a time‐to‐event endpoint might be explained by the effect of treatment on a mediator of interest, a variable that is measured longitudinally at planned visits throug...

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Veröffentlicht in:Statistics in medicine Jg. 38; H. 24; S. 4828 - 4840
Hauptverfasser: Vansteelandt, Stijn, Linder, Martin, Vandenberghe, Sjouke, Steen, Johan, Madsen, Jesper
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Wiley Subscription Services, Inc 30.10.2019
John Wiley and Sons Inc
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ISSN:0277-6715, 1097-0258, 1097-0258
Online-Zugang:Volltext
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