The feasibility of using mutation detection in ctDNA to assess tumor dynamics

For many decades it has been known that tumor DNA is shed into the blood. As a consequence of technological limitations, researchers were unable to comprehensively characterize circulating DNA. The advent of ultrasensitive and highly specific molecular assays has provided a comprehensive profile of...

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Veröffentlicht in:	International journal of cancer Jg. 140; H. 12; S. 2642 - 2647
Hauptverfasser:	Yi, Xin, Ma, Jianhui, Guan, Yanfang, Chen, Rongrong, Yang, Ling, Xia, Xuefeng
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Wiley Subscription Services, Inc 15.06.2017 John Wiley and Sons Inc
Schlagworte:	Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Biopsy Cancer ctDNA Deoxyribonucleic acid DNA DNA Mutational Analysis - methods DNA, Neoplasm - blood DNA, Neoplasm - genetics DNA, Neoplasm - isolation & purification Exosomes Exosomes - genetics Feasibility Studies Humans Invasiveness liquid biopsy Medical research Metastases Mini Review minimal‐invasive Mutation Neoplasms - classification Neoplasms - diagnosis Neoplasms - genetics Neoplastic Cells, Circulating - metabolism Predictive Value of Tests minimal-invasive ctDNA liquid biopsy
ISSN:	0020-7136, 1097-0215, 1097-0215
Online-Zugang:	Volltext
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