Clinical spectrum associated with MOG autoimmunity in adults: significance of sharing rodent MOG epitopes

The aim of this study was to report the clinical spectrum associated with antibodies to myelin oligodendrocyte glycoprotein (MOG) in adult patients, and to assess whether phenotypic variants are dependent on recognition of rodent MOG epitopes. We retrospectively analyzed the features, course and out...

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Bibliographic Details
Published in:	Journal of neurology Vol. 263; no. 7; pp. 1349 - 1360
Main Authors:	Sepúlveda, Maria, Armangue, Thaís, Martinez-Hernandez, Eugenia, Arrambide, Georgina, Sola-Valls, Nuria, Sabater, Lidia, Téllez, Nieves, Midaglia, Luciana, Ariño, Helena, Peschl, Patrick, Reindl, Markus, Rovira, Alex, Montalban, Xavier, Blanco, Yolanda, Dalmau, Josep, Graus, Francesc, Saiz, Albert
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2016 Springer Nature B.V
Subjects:	Adolescent Adult Adults Aged Animals Antibodies Aquaporin 4 - immunology Autoantibodies - blood Autoimmunity - physiology Brain - metabolism Disability Evaluation Encephalomyelitis Female Follow-Up Studies Glycoproteins HEK293 Cells Humans Magnetic Resonance Imaging Male Medicine Medicine & Public Health Middle Aged Myelin-Oligodendrocyte Glycoprotein - immunology Neurology Neuromyelitis Optica - blood Neuromyelitis Optica - pathology Neuromyelitis Optica - physiopathology Neuroradiology Neurosciences Original Communication Retrospective Studies Statistics, Nonparametric Young Adult Spain Immunohistochemistry Longitudinally extensive myelitis Antibodies to myelin oligodendrocyte glycoprotein MRI Optic neuritis Neuromyelitis optica Cell-based assays
ISSN:	0340-5354, 1432-1459
Online Access:	Get full text
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