Plasma Homocysteine Concentration is Associated with the Expression Level of Folate Receptor 3

Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer’s disease, thrombosis, neuropsychiatric illness and fractures. While several studies have reported that FOLR1 and FOLR2 import folic acid into cells, the role of FOL...

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Bibliographic Details
Published in:	Scientific Reports Vol. 10; no. 1; p. 10283
Main Authors:	Yoshitomi, Ren, Nakayama, Kai, Yamashita, Shuya, Kumazoe, Motofumi, Lin, Ting-An, Mei, Chen-Yi, Marugame, Yuki, Fujimura, Yoshinori, Maeda-Yamamoto, Mari, Kuriyama, Shinichi, Tachibana, Hirofumi
Format:	Journal Article
Language:	English
Published:	London Springer Science and Business Media LLC 24.06.2020 Nature Publishing Group UK Nature Publishing Group
Subjects:	631/80 692/4017 692/53 692/699 692/700 Acids Alzheimer's disease Carrier Proteins Carrier Proteins - blood Carrier Proteins - metabolism Cell growth Cohort Studies Cytotoxicity Dietary Supplements Ectopic expression Female Folic Acid Folic Acid - administration & dosage Folic Acid - metabolism Health risk assessment HEK293 Cells Homocysteine Homocysteine - blood Homocysteine - toxicity Humanities and Social Sciences Humans Male Mental disorders Middle Aged multidisciplinary Neurodegenerative diseases Neurotoxicity Neurotoxicity Syndromes Neurotoxicity Syndromes - etiology Neurotoxicity Syndromes - pathology Plasma Risk factors Science Science (multidisciplinary) Thromboembolism Thrombosis Vitamin B
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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