Salvia lachnostachys Benth has antitumor and chemopreventive effects against solid Ehrlich carcinoma

Salvia lachnostachys is an herbaceous plant with anti-inflammatory, analgesic and cytotoxic properties. This study investigated the antitumor effect of an ethanolic extract of Salvia lachnostachys leaves (EES) in a solid Ehrlich carcinoma model. Ehrlich cells were inoculated subcutaneously in the ri...

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Veröffentlicht in:	Molecular Biology Reports Jg. 46; H. 5; S. 4827 - 4841
Hauptverfasser:	Corso, Claudia Rita, Stipp, Maria Carolina, Adami, Eliana Rezende, da Silva, Luisa Mota, Mariott, Marihá, de Andrade, Sergio Faloni, de Souza Ramos, Edneia Amancio, Klassen, Giseli, Beltrame, Olair Carlos, Queiroz-Telles, José Ederaldo, de Oliveira, Cristhian Santos, Stefanello, Maria Élida Alves, Acco, Alexandra
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Dordrecht Springer Science and Business Media LLC 01.10.2019 Springer Netherlands Springer Nature B.V
Schlagworte:	Acute toxicity Analgesics Animal Anatomy Animal Biochemistry Animals Anticarcinogenic Agents Anticarcinogenic Agents - chemistry Anticarcinogenic Agents - pharmacology antineoplastic activity Antineoplastic Agents, Phytogenic Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - pharmacology Antioxidants Antitumor activity Biomedical and Life Sciences carcinoma Carcinoma, Ehrlich Tumor Carcinoma, Ehrlich Tumor - genetics Carcinoma, Ehrlich Tumor - metabolism Chemoprevention Chromatography, High Pressure Liquid Cyclin D1 Cyclin D1 - genetics Cyclin D1 - metabolism cyclins Cytotoxicity Female females Gene Expression Regulation, Neoplastic Glutathione herbaceous plants Histology Inflammation Inoculation Interleukin 10 Life Sciences Lipid peroxidation Methotrexate Mice molecular biology Molecular Structure Morphology N-Acetylglucosaminidase necrosis neoplasm cells Original Article Oxidative Stress Oxidative Stress - drug effects Plant Extracts Plant Extracts - chemistry Plant Extracts - pharmacology Plant Leaves Plant Leaves - chemistry Reactive Oxygen Species Reactive Oxygen Species - metabolism Salvia Salvia - chemistry Superoxide dismutase toxicity testing Tumor necrosis factor-TNF Tumor necrosis factor-α Antiproliferative Inflammation Solid Ehrlich carcinoma Antitumor Cyclin D1 Salvia lachnostachys
ISSN:	0301-4851, 1573-4978, 1573-4978
Online-Zugang:	Volltext
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