NOX family NADPH oxidases in mammals: Evolutionary conservation and isoform-defining sequences

NADPH oxidases are superoxide-producing enzymes that play a role in host defense, biosynthetic pathways, as well as cellular signaling. Humans have 7 NOX isoforms (NOX1-5, DUOX1,2), while mice and rats lack NOX5 and therefore have only 6 NOX isoforms. Whether all human NOX isoforms or their subunits...

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Bibliographic Details
Published in:Redox biology Vol. 66; p. 102851
Main Authors: Nazari, Bahareh, Jaquet, Vincent, Krause, Karl-Heinz
Format: Journal Article
Language:English
Published: Elsevier B.V 01.10.2023
Elsevier
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ISSN:2213-2317, 2213-2317
Online Access:Get full text
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