Synergistic virulence of Porphyromonas gingivalis and Treponema denticola in a murine periodontitis model

Summary Chronic periodontitis is characterized by the destruction of the tissues supporting the teeth and has been associated with the presence of a subgingival polymicrobial biofilm containing Porphyromonas gingivalis and Treponema denticola. We have investigated the potential synergistic virulence...

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Bibliographic Details
Published in:	Molecular oral microbiology Vol. 26; no. 4; pp. 229 - 240
Main Authors:	Orth, R.K-H., O'Brien-Simpson, N.M., Dashper, S.G., Reynolds, E.C.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.08.2011
Subjects:	alveolar bone loss Alveolar Bone Loss - microbiology animal model Animal models Animals Biofilms Bone (alveolar) Bone loss chronic periodontitis Chronic Periodontitis - immunology Chronic Periodontitis - microbiology Cytokines Data processing Disease Models, Animal DNA, Bacterial - analysis gamma -Interferon Immune response Inoculation Interferon-gamma - biosynthesis Interleukin-4 - biosynthesis Leukocyte Count Lymphocytes T Mice Mice, Inbred BALB C Microbial Interactions - physiology Periodontitis Porphyromonas Porphyromonas gingivalis Porphyromonas gingivalis - immunology T-Lymphocytes - immunology Teeth Treponema Treponema denticola Treponema denticola - immunology Virulence
ISSN:	2041-1006, 2041-1014, 2041-1014
Online Access:	Get full text
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