PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity

Protein arginine methyltransferase 5 (PRMT5) controls diverse cellular processes and is implicated in cancer development and progression. Here, we report an inverse correlation between PRMT5 function and antitumor immunity. expression was associated with an antitumor immune gene signature in human m...

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Bibliographic Details

Published in:	Science translational medicine Vol. 12; no. 551
Main Authors:	Kim, Hyungsoo, Kim, Heejung, Feng, Yongmei, Li, Yan, Tamiya, Hironari, Tocci, Stefania, Ronai, Ze'ev A
Format:	Journal Article
Language:	English
Published:	United States 08.07.2020
ISSN:	1946-6242, 1946-6242
Online Access:	Get more information
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