High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

Individual reports suggest that the central nervous system (CNS) contains multiple immune cell types with diverse roles in tissue homeostasis, immune defense, and neurological diseases. It has been challenging to map leukocytes across the entire brain, and in particular in pathology, where phenotypi...

Full description

Bibliographic Details

Published in:	Immunity (Cambridge, Mass.) Vol. 48; no. 2; p. 380
Main Authors:	Mrdjen, Dunja, Pavlovic, Anto, Hartmann, Felix J, Schreiner, Bettina, Utz, Sebastian G, Leung, Brian P, Lelios, Iva, Heppner, Frank L, Kipnis, Jonathan, Merkler, Doron, Greter, Melanie, Becher, Burkhard
Format:	Journal Article
Language:	English
Published:	United States 20.02.2018
Subjects:	high-dimensional macrophages experimental autoimmune encephalomyelitis Alzheimer’s disease multiple sclerosis neurodegeneration aging mass cytometry microglia central nervous system
ISSN:	1097-4180, 1097-4180
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!