State of the Art Review: Depression, Stress, Anxiety, and Cardiovascular Disease

The notion that psychological states can influence physical health is hardly new, and perhaps nowhere has the mind-body connection been better studied than in cardiovascular disease (CVD). Recently, large prospective epidemiologic studies and smaller basic science studies have firmly established a c...

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Bibliographic Details
Published in:American journal of hypertension Vol. 28; no. 11; pp. 1295 - 1302
Main Authors: Cohen, Beth E., Edmondson, Donald, Kronish, Ian M.
Format: Journal Article
Language:English
Published: US Oxford University Press 01.11.2015
Series:Editor's choice
Subjects:
Anxiety
Anxiety - epidemiology
Anxiety - physiopathology
Anxiety - therapy
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - prevention & control
Cardiovascular Diseases - psychology
Comorbidity
Depression - epidemiology
Depression - physiopathology
Depression - therapy
Epidemiology
Humans
Psychological Techniques
Psychotropic Drugs - pharmacology
Risk Factors
State of the Art
Stress Disorders, Post-Traumatic - epidemiology
Stress Disorders, Post-Traumatic - physiopathology
Stress Disorders, Post-Traumatic - therapy
Stress, Psychological - epidemiology
Stress, Psychological - physiopathology
Stress, Psychological - therapy
PTSD
blood pressure
cardiovascular disease
stress
anxiety disorders
coronary heart disease
depression
hypertension
ISSN:0895-7061, 1941-7225, 1941-7225
Online Access:Get full text
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Summary:The notion that psychological states can influence physical health is hardly new, and perhaps nowhere has the mind-body connection been better studied than in cardiovascular disease (CVD). Recently, large prospective epidemiologic studies and smaller basic science studies have firmly established a connection between CVD and several psychological conditions, including depression, chronic psychological stress, posttraumatic stress disorder (PTSD), and anxiety. In addition, numerous clinical trials have been conducted to attempt to prevent or lessen the impact of these conditions on cardiovascular health. In this article, we review studies connecting depression, stress/PTSD, and anxiety to CVD, focusing on findings from the last 5 years. For each mental health condition, we first examine the epidemiologic evidence establishing a link with CVD. We then describe studies of potential underlying mechanisms and finally discuss treatment trials and directions for future research.
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ISSN:0895-7061
1941-7225
1941-7225
DOI:10.1093/ajh/hpv047