A Genomewide Association Study of Nicotine and Alcohol Dependence in Australian and Dutch Populations

Persistent tobacco use and excessive alcohol consumption are major public health concerns worldwide. Both alcohol and nicotine dependence (AD, ND) are genetically influenced complex disorders that exhibit a high degree of comorbidity. To identify gene variants contributing to one or both of these ad...

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Veröffentlicht in:	Twin research and human genetics Jg. 13; H. 1; S. 10 - 29
Hauptverfasser:	Lind, Penelope A, Macgregor, Stuart, Vink, Jacqueline M, Pergadia, Michele L, Hansell, Narelle K, de Moor, Marleen H. M, Smit, August B, Hottenga, Jouke-Jan, Richter, Melinda M, Heath, Andrew C, Martin, Nicholas G, Willemsen, Gonneke, de Geus, Eco J. C, Vogelzangs, Nicole, Penninx, Brenda W, Whitfield, John B, Montgomery, Grant W, Boomsma, Dorret I, Madden, Pamela A. F
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.02.2010
Schlagworte:	Adult Aged Alcoholism Alcoholism - epidemiology Alcoholism - genetics Australia - epidemiology Case-Control Studies Comorbidity DEAD-box RNA Helicases - genetics Diseases in Twins - epidemiology Diseases in Twins - genetics Female Genetic Predisposition to Disease Genome-Wide Association Study GTPase-Activating Proteins - genetics Humans Male Middle Aged Netherlands - epidemiology Polymorphism, Single Nucleotide Protein Serine-Threonine Kinases - genetics Proto-Oncogene Proteins - genetics Registries rhoA GTP-Binding Protein Statistics Substance abuse Tobacco Use Disorder - epidemiology Tobacco Use Disorder - genetics Twins Australia Netherlands
ISSN:	1832-4274
Online-Zugang:	Volltext
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