Influence of congenital human cytomegalovirus infection and the NKG2C genotype on NK‐cell subset distribution in children

Human cytomegalovirus (HCMV) has been reported to reshape the NK‐cell receptor (NKR) distribution, promoting an expansion of CD94/NKG2C+ NK and T cells. The role of NK cells in congenital HCMV infection is ill‐defined. Here we studied the expression of NKR (i.e., NKG2C, NKG2A, LILRB1, CD161) and the...

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Bibliographic Details
Published in:	European journal of immunology Vol. 42; no. 12; pp. 3256 - 3266
Main Authors:	Noyola, Daniel E., Fortuny, Claudia, Muntasell, Aura, Noguera‐Julian, Antoni, Muñoz‐Almagro, Carmen, Alarcón, Ana, Juncosa, Teresa, Moraru, Manuela, Vilches, Carlos, López‐Botet, Miguel
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01.12.2012
Subjects:	Antigens, Differentiation - biosynthesis Antigens, Differentiation - genetics Antigens, Differentiation - immunology Cells Children & youth Congenital infection Cytomegalovirus Cytomegalovirus - genetics Cytomegalovirus - immunology Cytomegalovirus Infections - blood Cytomegalovirus Infections - congenital Cytomegalovirus Infections - genetics Cytomegalovirus Infections - immunology Female Gene Deletion Gene Dosage - immunology Gene Expression Regulation - genetics Gene Expression Regulation - immunology Genotype & phenotype Homeostasis - genetics Homeostasis - immunology Human cytomegalovirus Humans Immunology Infant Infant, Newborn Infections Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Lymphocyte Count Male NK Cell Lectin-Like Receptor Subfamily C - biosynthesis NK Cell Lectin-Like Receptor Subfamily C - immunology NK cells NKG2C
ISSN:	0014-2980, 1521-4141, 1521-4141
Online Access:	Get full text
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