Thermal and magnetic properties of chitosan-iron oxide nanoparticles

•Chitosan is widely used for biomedical applications.•Chitosan-iron oxide nanoparticles are suitable for magnetic hyperthermia.•Chitosan coating does not affect the properties of iron oxide nanoparticles.•Chitosan-iron oxide nanoparticles have a nanometric hydrodynamic diameter. Chitosan is a biopol...

Full description

Saved in:
Bibliographic Details
Published in:Carbohydrate polymers Vol. 149; pp. 382 - 390
Main Authors: Soares, Paula I.P., Machado, Diana, Laia, César, Pereira, Laura C.J., Coutinho, Joana T., Ferreira, Isabel M.M., Novo, Carlos M.M., Borges, João Paulo
Format: Journal Article
Language:English
Published: England Elsevier Ltd 20.09.2016
Subjects:
biocompatibility
biopolymers
chemical composition
chemical precipitation
Chitosan
Chitosan - chemistry
coatings
crystal structure
drug delivery systems
fever
heat
hydrodynamics
Iron oxide nanoparticles
magnetic fields
Magnetic hyperthermia
Magnetic Phenomena
magnetic properties
Magnetite
Magnetite Nanoparticles - chemistry
Molecular Weight
nanocomposites
nanoparticles
Temperature
thermal degradation
tissue engineering
tissue repair
Magnetic hyperthermia
Magnetite
Chitosan
Iron oxide nanoparticles
ISSN:0144-8617, 1879-1344, 1879-1344
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•Chitosan is widely used for biomedical applications.•Chitosan-iron oxide nanoparticles are suitable for magnetic hyperthermia.•Chitosan coating does not affect the properties of iron oxide nanoparticles.•Chitosan-iron oxide nanoparticles have a nanometric hydrodynamic diameter. Chitosan is a biopolymer widely used for biomedical applications such as drug delivery systems, wound healing, and tissue engineering. Chitosan can be used as coating for other types of materials such as iron oxide nanoparticles, improving its biocompatibility while extending its range of applications. In this work iron oxide nanoparticles (Fe3O4 NPs) produced by chemical precipitation and thermal decomposition and coated with chitosan with different molecular weights were studied. Basic characterization on bare and chitosan-Fe3O4 NPs was performed demonstrating that chitosan does not affect the crystallinity, chemical composition, and superparamagnetic properties of the Fe3O4 NPs, and also the incorporation of Fe3O4 NPs into chitosan nanoparticles increases the later hydrodynamic diameter without compromising its physical and chemical properties. The nano-composite was tested for magnetic hyperthermia by applying an alternating current magnetic field to the samples demonstrating that the heating ability of the Fe3O4 NPs was not significantly affected by chitosan.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0144-8617
1879-1344
1879-1344
DOI:10.1016/j.carbpol.2016.04.123