The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model

Increasing evidence suggests that B lymphocytes play a central role in inhibiting the immune response against certain tumors, but the underlying mechanisms by which B cells facilitate tumor growth are still poorly understood. In this study, we investigated how the presence or absence of B cells affe...

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Veröffentlicht in:Cancer Immunology, Immunotherapy Jg. 60; H. 5; S. 609 - 619
Hauptverfasser: Tadmor, Tamar, Zhang, Yu, Cho, Hyun-Mi, Podack, Eckhard R., Rosenblatt, Joseph D.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Berlin/Heidelberg Springer-Verlag 01.05.2011
Springer Nature B.V
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ISSN:0340-7004, 1432-0851, 1432-0851
Online-Zugang:Volltext
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