Expansion of SARS-CoV-2-Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in late 2019 and has since become a global pandemic. Pathogen-specific Abs are typically a major predictor of protective immunity, yet human B cell and Ab responses during COVID-19 ar...

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Veröffentlicht in:	The Journal of immunology (1950) Jg. 205; H. 9; S. 2437
Hauptverfasser:	Varnaitė, Renata, García, Marina, Glans, Hedvig, Maleki, Kimia T, Sandberg, John Tyler, Tynell, Janne, Christ, Wanda, Lagerqvist, Nina, Asgeirsson, Hilmir, Ljunggren, Hans-Gustaf, Ahlén, Gustaf, Frelin, Lars, Sällberg, Matti, Blom, Kim, Klingström, Jonas, Gredmark-Russ, Sara
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.11.2020
Schlagworte:	Adult Aged Antibodies, Neutralizing - immunology Antibodies, Viral - immunology B-Lymphocytes - immunology Betacoronavirus - immunology Biomarkers - blood C-Reactive Protein - analysis Cohort Studies Coronavirus Infections - epidemiology Coronavirus Infections - immunology Coronavirus Infections - virology Coronavirus Nucleocapsid Proteins COVID-19 Female Hospitalization Humans Immunoglobulin A - blood Immunoglobulin G - blood Immunoglobulin M - blood Interleukin-6 - blood Lymphocyte Activation Male Middle Aged Nucleocapsid Proteins - immunology Pandemics Phosphoproteins Pneumonia, Viral - epidemiology Pneumonia, Viral - immunology Pneumonia, Viral - virology SARS-CoV-2 Sweden - epidemiology Sweden
ISSN:	1550-6606, 1550-6606
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