Transmission of intestinal Bifidobacterium longum subsp. longum strains from mother to infant, determined by multilocus sequencing typing and amplified fragment length polymorphism

The gastrointestinal tracts of neonates are colonized by bacteria immediately after birth. It has been discussed that the intestinal microbiota of neonates includes strains transferred from the mothers. Although some studies have indicated possible bacterial transfer from the mother to the newborn,...

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Published in:	Applied and environmental microbiology Vol. 77; no. 19; p. 6788
Main Authors:	Makino, Hiroshi, Kushiro, Akira, Ishikawa, Eiji, Muylaert, Delphine, Kubota, Hiroyuki, Sakai, Takafumi, Oishi, Kenji, Martin, Rocio, Ben Amor, Kaouther, Oozeer, Raish, Knol, Jan, Tanaka, Ryuichiro
Format:	Journal Article
Language:	English
Published:	United States 01.10.2011
Subjects:	Amplified Fragment Length Polymorphism Analysis - methods Bifidobacteriales Infections - microbiology Bifidobacteriales Infections - transmission Bifidobacterium - classification Bifidobacterium - genetics Bifidobacterium - isolation & purification Carrier State - microbiology Carrier State - transmission Cluster Analysis Feces - microbiology Genotype Humans Infant Molecular Typing - methods Multilocus Sequence Typing - methods
ISSN:	1098-5336, 1098-5336
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Abstract	The gastrointestinal tracts of neonates are colonized by bacteria immediately after birth. It has been discussed that the intestinal microbiota of neonates includes strains transferred from the mothers. Although some studies have indicated possible bacterial transfer from the mother to the newborn, this is the first report confirming the transfer of bifidobacteria at the strain level. Here, we investigated the mother-to-infant transmission of Bifidobacterium longum subsp. longum by genotyping bacterial isolates from the feces of mothers before delivery and of their infants after delivery. Two hundred seven isolates from 8 pairs of mothers and infants were discriminated by multilocus sequencing typing (MLST) and amplified fragment length polymorphism (AFLP) analysis. By both methods, 11 strains of B. longum subsp. longum were found to be monophyletic for the feces of the mother and her infant. This finding confirms that these strains were transferred from the intestine of the mother to that of the infant. These strains were found in the first feces (meconium) of the infant and in the feces at days 3, 7, 30, and 90 after birth, indicating that they stably colonize the infant's intestine immediately after birth. The strains isolated from each family did not belong to clusters derived from any of the other families, suggesting that each mother-infant pair might have unique family-specific strains.
AbstractList	The gastrointestinal tracts of neonates are colonized by bacteria immediately after birth. It has been discussed that the intestinal microbiota of neonates includes strains transferred from the mothers. Although some studies have indicated possible bacterial transfer from the mother to the newborn, this is the first report confirming the transfer of bifidobacteria at the strain level. Here, we investigated the mother-to-infant transmission of Bifidobacterium longum subsp. longum by genotyping bacterial isolates from the feces of mothers before delivery and of their infants after delivery. Two hundred seven isolates from 8 pairs of mothers and infants were discriminated by multilocus sequencing typing (MLST) and amplified fragment length polymorphism (AFLP) analysis. By both methods, 11 strains of B. longum subsp. longum were found to be monophyletic for the feces of the mother and her infant. This finding confirms that these strains were transferred from the intestine of the mother to that of the infant. These strains were found in the first feces (meconium) of the infant and in the feces at days 3, 7, 30, and 90 after birth, indicating that they stably colonize the infant's intestine immediately after birth. The strains isolated from each family did not belong to clusters derived from any of the other families, suggesting that each mother-infant pair might have unique family-specific strains. The gastrointestinal tracts of neonates are colonized by bacteria immediately after birth. It has been discussed that the intestinal microbiota of neonates includes strains transferred from the mothers. Although some studies have indicated possible bacterial transfer from the mother to the newborn, this is the first report confirming the transfer of bifidobacteria at the strain level. Here, we investigated the mother-to-infant transmission of Bifidobacterium longum subsp. longum by genotyping bacterial isolates from the feces of mothers before delivery and of their infants after delivery. Two hundred seven isolates from 8 pairs of mothers and infants were discriminated by multilocus sequencing typing (MLST) and amplified fragment length polymorphism (AFLP) analysis. By both methods, 11 strains of B. longum subsp. longum were found to be monophyletic for the feces of the mother and her infant. This finding confirms that these strains were transferred from the intestine of the mother to that of the infant. These strains were found in the first feces (meconium) of the infant and in the feces at days 3, 7, 30, and 90 after birth, indicating that they stably colonize the infant's intestine immediately after birth. The strains isolated from each family did not belong to clusters derived from any of the other families, suggesting that each mother-infant pair might have unique family-specific strains.The gastrointestinal tracts of neonates are colonized by bacteria immediately after birth. It has been discussed that the intestinal microbiota of neonates includes strains transferred from the mothers. Although some studies have indicated possible bacterial transfer from the mother to the newborn, this is the first report confirming the transfer of bifidobacteria at the strain level. Here, we investigated the mother-to-infant transmission of Bifidobacterium longum subsp. longum by genotyping bacterial isolates from the feces of mothers before delivery and of their infants after delivery. Two hundred seven isolates from 8 pairs of mothers and infants were discriminated by multilocus sequencing typing (MLST) and amplified fragment length polymorphism (AFLP) analysis. By both methods, 11 strains of B. longum subsp. longum were found to be monophyletic for the feces of the mother and her infant. This finding confirms that these strains were transferred from the intestine of the mother to that of the infant. These strains were found in the first feces (meconium) of the infant and in the feces at days 3, 7, 30, and 90 after birth, indicating that they stably colonize the infant's intestine immediately after birth. The strains isolated from each family did not belong to clusters derived from any of the other families, suggesting that each mother-infant pair might have unique family-specific strains.
Author	Sakai, Takafumi Martin, Rocio Kushiro, Akira Ben Amor, Kaouther Oozeer, Raish Muylaert, Delphine Ishikawa, Eiji Oishi, Kenji Makino, Hiroshi Tanaka, Ryuichiro Knol, Jan Kubota, Hiroyuki
Author_xml	– sequence: 1 givenname: Hiroshi surname: Makino fullname: Makino, Hiroshi email: hiroshi.makino@yher.be organization: Yakult Honsha European Research Center for Microbiology, ESV, Technologiepark 4, 9052 Ghent-Zwijnaarde, Belgium. hiroshi.makino@yher.be – sequence: 2 givenname: Akira surname: Kushiro fullname: Kushiro, Akira – sequence: 3 givenname: Eiji surname: Ishikawa fullname: Ishikawa, Eiji – sequence: 4 givenname: Delphine surname: Muylaert fullname: Muylaert, Delphine – sequence: 5 givenname: Hiroyuki surname: Kubota fullname: Kubota, Hiroyuki – sequence: 6 givenname: Takafumi surname: Sakai fullname: Sakai, Takafumi – sequence: 7 givenname: Kenji surname: Oishi fullname: Oishi, Kenji – sequence: 8 givenname: Rocio surname: Martin fullname: Martin, Rocio – sequence: 9 givenname: Kaouther surname: Ben Amor fullname: Ben Amor, Kaouther – sequence: 10 givenname: Raish surname: Oozeer fullname: Oozeer, Raish – sequence: 11 givenname: Jan surname: Knol fullname: Knol, Jan – sequence: 12 givenname: Ryuichiro surname: Tanaka fullname: Tanaka, Ryuichiro
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/21821739$$D View this record in MEDLINE/PubMed
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References	7501463 - Nucleic Acids Res. 1995 Nov 11;23(21):4407-14 11957119 - J Infect Chemother. 2002 Mar;8(1):43-9 19088308 - Appl Environ Microbiol. 2009 Feb;75(4):965-9 19719575 - FEMS Microbiol Ecol. 2003 Nov 1;46(2):213-9 17332189 - Pediatrics. 2007 Mar;119(3):e724-32 20421439 - J Clin Microbiol. 2010 Jul;48(7):2350-6 17158978 - Int J Syst Evol Microbiol. 2006 Dec;56(Pt 12):2783-92 10461381 - J Eukaryot Microbiol. 1999 Jul-Aug;46(4):327-38 10508082 - Appl Environ Microbiol. 1999 Oct;65(10):4506-12 11876360 - Syst Appl Microbiol. 2001 Dec;24(4):520-38 16506376 - Hepatogastroenterology. 2006 Jan-Feb;53(67):55-9 16887708 - Anaerobe. 2003 Oct;9(5):219-29 14752001 - Bioinformatics. 2004 Mar 22;20(5):798-9 8757752 - Microbiology. 1996 Jul;142 ( Pt 7):1881-93 19060069 - Int J Syst Evol Microbiol. 2008 Dec;58(Pt 12):2839-49 15591256 - J Med Microbiol. 2005 Jan;54(Pt 1):55-61 20890213 - J Pediatr Gastroenterol Nutr. 2010 Nov;51(5):653-60 15186354 - Environ Microbiol. 2004 Jul;6(7):754-9 9858460 - Microbiol Immunol. 1998;42(10):661-7 18338233 - Antonie Van Leeuwenhoek. 2008 Jun;94(1):35-50 20176122 - Anaerobe. 2010 Jun;16(3):307-10 19114515 - Appl Environ Microbiol. 2009 Mar;75(5):1291-300 14711639 - Appl Environ Microbiol. 2004 Jan;70(1):167-73 17704267 - Appl Environ Microbiol. 2007 Oct;73(20):6601-11 17596738 - Neonatology. 2007;92(1):64-6 14657823 - J Pediatr. 2003 Dec;143(6):754-8 8255788 - Nucleic Acids Res. 1993 Nov 11;21(22):5279-80 11150002 - J Allergy Clin Immunol. 2001 Jan;107(1):129-34 16650661 - Vet Microbiol. 2006 Aug 25;116(1-3):158-65 19430378 - Pediatr Res. 2009 Jun;65(6):669-74 12583961 - Lancet. 2003 Feb 8;361(9356):512-9 20060895 - Res Microbiol. 2010 Mar;161(2):82-90 21300508 - Syst Appl Microbiol. 2011 Apr;34(2):148-55 19542117 - Int J Syst Evol Microbiol. 2009 Jul;59(Pt 7):1771-86 14766571 - Appl Environ Microbiol. 2004 Feb;70(2):913-20
References_xml	– reference: 21300508 - Syst Appl Microbiol. 2011 Apr;34(2):148-55 – reference: 11150002 - J Allergy Clin Immunol. 2001 Jan;107(1):129-34 – reference: 8757752 - Microbiology. 1996 Jul;142 ( Pt 7):1881-93 – reference: 9858460 - Microbiol Immunol. 1998;42(10):661-7 – reference: 10461381 - J Eukaryot Microbiol. 1999 Jul-Aug;46(4):327-38 – reference: 14657823 - J Pediatr. 2003 Dec;143(6):754-8 – reference: 16650661 - Vet Microbiol. 2006 Aug 25;116(1-3):158-65 – reference: 8255788 - Nucleic Acids Res. 1993 Nov 11;21(22):5279-80 – reference: 20890213 - J Pediatr Gastroenterol Nutr. 2010 Nov;51(5):653-60 – reference: 20176122 - Anaerobe. 2010 Jun;16(3):307-10 – reference: 20060895 - Res Microbiol. 2010 Mar;161(2):82-90 – reference: 19088308 - Appl Environ Microbiol. 2009 Feb;75(4):965-9 – reference: 10508082 - Appl Environ Microbiol. 1999 Oct;65(10):4506-12 – reference: 11876360 - Syst Appl Microbiol. 2001 Dec;24(4):520-38 – reference: 15186354 - Environ Microbiol. 2004 Jul;6(7):754-9 – reference: 18338233 - Antonie Van Leeuwenhoek. 2008 Jun;94(1):35-50 – reference: 17332189 - Pediatrics. 2007 Mar;119(3):e724-32 – reference: 19060069 - Int J Syst Evol Microbiol. 2008 Dec;58(Pt 12):2839-49 – reference: 16887708 - Anaerobe. 2003 Oct;9(5):219-29 – reference: 20421439 - J Clin Microbiol. 2010 Jul;48(7):2350-6 – reference: 17704267 - Appl Environ Microbiol. 2007 Oct;73(20):6601-11 – reference: 15591256 - J Med Microbiol. 2005 Jan;54(Pt 1):55-61 – reference: 7501463 - Nucleic Acids Res. 1995 Nov 11;23(21):4407-14 – reference: 17158978 - Int J Syst Evol Microbiol. 2006 Dec;56(Pt 12):2783-92 – reference: 19430378 - Pediatr Res. 2009 Jun;65(6):669-74 – reference: 11957119 - J Infect Chemother. 2002 Mar;8(1):43-9 – reference: 12583961 - Lancet. 2003 Feb 8;361(9356):512-9 – reference: 19114515 - Appl Environ Microbiol. 2009 Mar;75(5):1291-300 – reference: 16506376 - Hepatogastroenterology. 2006 Jan-Feb;53(67):55-9 – reference: 14766571 - Appl Environ Microbiol. 2004 Feb;70(2):913-20 – reference: 14711639 - Appl Environ Microbiol. 2004 Jan;70(1):167-73 – reference: 19719575 - FEMS Microbiol Ecol. 2003 Nov 1;46(2):213-9 – reference: 19542117 - Int J Syst Evol Microbiol. 2009 Jul;59(Pt 7):1771-86 – reference: 14752001 - Bioinformatics. 2004 Mar 22;20(5):798-9 – reference: 17596738 - Neonatology. 2007;92(1):64-6
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Snippet	The gastrointestinal tracts of neonates are colonized by bacteria immediately after birth. It has been discussed that the intestinal microbiota of neonates...
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SubjectTerms	Amplified Fragment Length Polymorphism Analysis - methods Bifidobacteriales Infections - microbiology Bifidobacteriales Infections - transmission Bifidobacterium - classification Bifidobacterium - genetics Bifidobacterium - isolation & purification Carrier State - microbiology Carrier State - transmission Cluster Analysis Feces - microbiology Genotype Humans Infant Molecular Typing - methods Multilocus Sequence Typing - methods
Title	Transmission of intestinal Bifidobacterium longum subsp. longum strains from mother to infant, determined by multilocus sequencing typing and amplified fragment length polymorphism
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