Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy

We report here on a first study using synchrotron radiation-based Fourier transform infrared microspectroscopy and imaging to investigate HT1080 human fibrosarcoma cells grown onto different-aged type I collagen networks. Spectral images were analyzed with k-means and fuzzy C-means (FCM) clustering...

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Bibliographic Details

Published in:	Journal of biomedical optics Vol. 19; no. 11; p. 111612
Main Authors:	Guilbert, Marie, Eklouh-Molinier, Christophe, Wehbe, Katia, Sulé-Suso, Josep, Yang, Ying, Cinque, Gianfelice, Jeannesson, Pierre, Sockalingum, Ganesh D
Format:	Journal Article
Language:	English
Published:	United States 01.11.2014
Subjects:	Algorithms Animals Biomarkers, Tumor - chemistry Biomarkers, Tumor - metabolism Cell Line, Tumor Cluster Analysis Collagen Type I - chemistry Collagen Type I - metabolism Neoplasms - chemistry Neoplasms - metabolism Rats Rats, Sprague-Dawley Single-Cell Analysis - methods Spectroscopy, Fourier Transform Infrared - methods Synchrotrons
ISSN:	1560-2281, 1560-2281
Online Access:	Get more information
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