The myotomal diwanka (lh3) glycosyltransferase and type XVIII collagen are critical for motor growth cone migration

The initial migration of motor growth cones from the spinal cord into the periphery requires extrinsic cues, yet their identities are largely unknown. In zebrafish diwanka mutants, motor growth cones are motile but fail to pioneer into the periphery. Here, we report on the positional cloning of diwa...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Jg. 50; H. 5; S. 683
Hauptverfasser:	Schneider, Valerie A, Granato, Michael
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.06.2006
Schlagworte:	Animals Cell Movement - physiology Cloning, Molecular Collagen Type XVIII - metabolism Collagen Type XVIII - physiology Embryo, Nonmammalian - cytology Embryo, Nonmammalian - enzymology Extracellular Matrix - enzymology Gene Expression Regulation, Developmental Gene Expression Regulation, Enzymologic Glycosyltransferases - chemistry Glycosyltransferases - genetics Glycosyltransferases - physiology Growth Cones - enzymology Growth Cones - ultrastructure HeLa Cells Humans Microscopy, Electron Molecular Sequence Data Motor Neurons - enzymology Motor Neurons - ultrastructure Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase - chemistry Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase - genetics Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase - physiology Protein Structure, Tertiary Zebrafish Zebrafish Proteins - chemistry Zebrafish Proteins - genetics Zebrafish Proteins - physiology
ISSN:	0896-6273
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