miR-365-3p mediates BCL11A and SOX6 erythroid-specific coregulation: A new player in HbF activation

Hemoglobin switching is a complex biological process not yet fully elucidated. The mechanism regulating the suppression of fetal hemoglobin (HbF) expression is of particular interest because of the positive impact of HbF on the course of diseases such as β-thalassemia and sickle cell disease, heredi...

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Bibliographic Details
Published in:	Molecular therapy. Nucleic acids Vol. 34; p. 102025
Main Authors:	Simbula, Michela, Manchinu, Maria Francesca, Mingoia, Maura, Pala, Mauro, Asunis, Isadora, Caria, Cristian Antonio, Perseu, Lucia, Shah, Manan, Crossley, Merlin, Moi, Paolo, Ristaldi, Maria Serafina
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 12.12.2023 American Society of Gene & Cell Therapy Elsevier
Subjects:	BCL11A gene expression miR-365-3p Non-coding RNAs Original SOX6 β-hemoglobinopathies γ-globin ε-globin Non-coding RNAs BCL11A miR-365-3p ε-globin SOX6 γ-globin β-hemoglobinopathies gene expression
ISSN:	2162-2531, 2162-2531
Online Access:	Get full text
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