Regulation and Functions of the ER-Associated Nrf1 Transcription Factor

Nrf1 is a member of the nuclear erythroid 2-like family of transcription factors that regulate stress-responsive gene expression in animals. Newly synthesized Nrf1 is targeted to the endoplasmic reticulum (ER) where it is -glycosylated. -glycosylated Nrf1 is trafficked to the cytosol by the ER-assoc...

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Bibliographic Details

Published in:	Cold Spring Harbor perspectives in biology Vol. 15; no. 1
Main Authors:	Ruvkun, Gary, Lehrbach, Nicolas
Format:	Journal Article
Language:	English
Published:	United States 01.01.2023
Subjects:	Animals Endoplasmic Reticulum - metabolism Gene Expression Regulation Nuclear Respiratory Factor 1 Proteasome Endopeptidase Complex - metabolism Proteolysis Transcription Factors - metabolism
ISSN:	1943-0264, 1943-0264
Online Access:	Get more information
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