La Crosse Encephalitis Surveillance using Single Versus Paired Serologic Testing

Summary We evaluated the validity of single versus paired serologic testing for La Crosse virus (LACV) encephalitis surveillance. Compared with paired serology, a single positive IgG or IgM immunoflourescent antibody titre appears useful for LACV encephalitis surveillance with sensitivity, 75%; spec...

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Bibliographic Details
Published in:Zoonoses and public health Vol. 59; no. 3; pp. 181 - 183
Main Authors: Murphree, R., Dunn, J. R., Schaffner, W., Jones, T. F.
Format: Journal Article
Language:English
Published: Oxford, UK Blackwell Publishing Ltd 01.05.2012
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
analysis
Animal diseases
Animals
Antibodies, Viral
Antibodies, Viral - analysis
Antibodies, Viral - immunology
Antigens, Viral
Antigens, Viral - analysis
Antigens, Viral - immunology
Blood tests
California encephalitis orthobunyavirus
Child
Child, Preschool
diagnosis
encephalitis
Encephalitis, California
Encephalitis, California - diagnosis
Encephalitis, California - immunology
Encephalitis, California - virology
epidemiology
Female
Fluorescent Antibody Technique
Hospitalization
Hospitalization - statistics & numerical data
Humans
immunoglobulin G
Immunoglobulin G - analysis
immunoglobulin M
Immunoglobulin M - analysis
immunologic techniques
immunology
Infant
isolation & purification
La Crosse virus
La Crosse virus - immunology
La Crosse virus - isolation & purification
Male
Medical diagnosis
methods
Middle Aged
monitoring
Predictive Value of Tests
Reproducibility of Results
Sentinel Surveillance
Serologic Tests
Serologic Tests - methods
statistics & numerical data
surveillance
Tennessee
Tennessee - epidemiology
Viral infections
virology
Young Adult
Tennessee
ISSN:1863-1959, 1863-2378, 1863-2378
Online Access:Get full text
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Summary:Summary We evaluated the validity of single versus paired serologic testing for La Crosse virus (LACV) encephalitis surveillance. Compared with paired serology, a single positive IgG or IgM immunoflourescent antibody titre appears useful for LACV encephalitis surveillance with sensitivity, 75%; specificity, 98%; positive predictive value, 95%; and overall test efficiency 92%.
Bibliography:istex:AA23EA2DDFEC7A4A60D72ED17B4FADB67612A38E
ark:/67375/WNG-0J9Q8Q8H-P
ArticleID:ZPH1433
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ISSN:1863-1959
1863-2378
1863-2378
DOI:10.1111/j.1863-2378.2011.01433.x