Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression

Macrophages constitute a major component of tumor-infiltrating immune cells. M2 macrophages have been reported to promote tumor progression through promoting tumor angiogenesis and metastasis and regulating T-cell function. Here, we identified a protumorigenic subset of macrophages that constitutive...

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Bibliographic Details
Published in:	Oncogenesis (New York, NY) Vol. 7; no. 5; pp. 41 - 11
Main Authors:	Wang, Furong, Li, Bin, Wei, Yucai, Zhao, Yang, Wang, Li, Zhang, Peng, Yang, Jinwei, He, Wenting, Chen, Hao, Jiao, Zuoyi, Li, Yumin
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 25.05.2018 Nature Publishing Group
Subjects:	13/31 38/77 631/250/251 631/67/1059/2325 Angiogenesis Apoptosis CD8 antigen Cell Biology Cell death Chemokines Exosomes Gastric cancer Human Genetics Immune response Immunosuppressive agents Immunotherapy Interleukin 10 Interleukin 12 Internal Medicine Lymphocytes T Macrophages Major histocompatibility complex Medicine Medicine & Public Health Metastases Monocytes Oncology Ovalbumin PD-1 protein Phenotypes Recovery of function T cell receptors Tumor-infiltrating lymphocytes
ISSN:	2157-9024, 2157-9024
Online Access:	Get full text
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