Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation

Nuclear receptor crosstalk can be defined as the interplay between different nuclear receptors or between their overlapping signalling pathways. A subset of nuclear receptors (such as PPARs and RARs) engage in the formation of well-characterized 'typical' heterodimers with RXR. 'Atypi...

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Bibliographic Details
Published in:	Nature reviews. Endocrinology Vol. 16; no. 7; pp. 363 - 377
Main Authors:	De Bosscher, Karolien, Desmet, Sofie J, Clarisse, Dorien, Estébanez-Perpiña, Eva, Brunsveld, Luc
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.07.2020
Subjects:	Animals Bile Drugs Gene expression Hormones Humans Ligands Medical innovations Nuclear receptors Peroxisome proliferator-activated receptors Physiology Protein Binding - physiology Protein Multimerization - physiology Proteins Receptor Cross-Talk - physiology Receptors, Cytoplasmic and Nuclear - metabolism Receptors, Cytoplasmic and Nuclear - physiology Retinoid X receptors Signal transduction Signal Transduction - physiology Therapies, Investigational - methods Therapies, Investigational - trends Transcription Transcription Factors - metabolism Transcription Factors - physiology Vitamin E
ISSN:	1759-5029, 1759-5037, 1759-5037
Online Access:	Get full text
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