Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation

Nuclear receptor crosstalk can be defined as the interplay between different nuclear receptors or between their overlapping signalling pathways. A subset of nuclear receptors (such as PPARs and RARs) engage in the formation of well-characterized 'typical' heterodimers with RXR. 'Atypi...

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Veröffentlicht in:	Nature reviews. Endocrinology Jg. 16; H. 7; S. 363 - 377
Hauptverfasser:	De Bosscher, Karolien, Desmet, Sofie J, Clarisse, Dorien, Estébanez-Perpiña, Eva, Brunsveld, Luc
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Nature Publishing Group 01.07.2020
Schlagworte:	Animals Bile Drugs Gene expression Hormones Humans Ligands Medical innovations Nuclear receptors Peroxisome proliferator-activated receptors Physiology Protein Binding - physiology Protein Multimerization - physiology Proteins Receptor Cross-Talk - physiology Receptors, Cytoplasmic and Nuclear - metabolism Receptors, Cytoplasmic and Nuclear - physiology Retinoid X receptors Signal transduction Signal Transduction - physiology Therapies, Investigational - methods Therapies, Investigational - trends Transcription Transcription Factors - metabolism Transcription Factors - physiology Vitamin E
ISSN:	1759-5029, 1759-5037, 1759-5037
Online-Zugang:	Volltext
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